Gene description for GLDC
Gene name	glycine dehydrogenase (decarboxylating)
Gene symbol	GLDC
Other names/aliases	GCE GCSP HYGN1
Species	Homo sapiens
Database cross references - GLDC
ExoCarta	ExoCarta_2731
Vesiclepedia	VP_2731
Entrez Gene	2731
HGNC	4313
MIM	238300
UniProt	P23378
GLDC identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells	Unpublished / Not applicable

Gene ontology annotations for GLDC

Molecular Function     glycine dehydrogenase (decarboxylating) activity GO:0004375 IBA     glycine dehydrogenase (decarboxylating) activity GO:0004375 IDA     electron transfer activity GO:0009055 TAS     glycine binding GO:0016594 IBA     lyase activity GO:0016829 IEA     pyridoxal phosphate binding GO:0030170 IBA     protein homodimerization activity GO:0042803 ISS     pyridoxal binding GO:0070280 ISS Biological Process     glycine catabolic process GO:0006546 IDA     glycine decarboxylation via glycine cleavage system GO:0019464 IBA     response to methylamine GO:0036255 ISS     response to lipoic acid GO:1903442 ISS     cellular response to leukemia inhibitory factor GO:1990830 IEA Subcellular Localization     nucleoplasm GO:0005654 IDA     mitochondrion GO:0005739 HTP     mitochondrion GO:0005739 IBA     mitochondrion GO:0005739 IDA     mitochondrial matrix GO:0005759 TAS     plasma membrane GO:0005886 IDA     glycine cleavage complex GO:0005960 IBA