Gene description for SLC5A5
Gene name	solute carrier family 5 (sodium/iodide cotransporter), member 5
Gene symbol	SLC5A5
Other names/aliases	NIS TDH1
Species	Homo sapiens
Database cross references - SLC5A5
ExoCarta	ExoCarta_6528
Vesiclepedia	VP_6528
Entrez Gene	6528
HGNC	11040
MIM	601843
UniProt	Q92911
SLC5A5 identified in sEVs derived from the following tissue/cell type
Saliva	19199708

Gene ontology annotations for SLC5A5

Molecular Function     protein binding GO:0005515 IPI     sodium:iodide symporter activity GO:0008507 IBA     sodium:iodide symporter activity GO:0008507 IDA     sodium:iodide symporter activity GO:0008507 IMP     sodium:iodide symporter activity GO:0008507 TAS     iodide transmembrane transporter activity GO:0015111 IDA     iodide transmembrane transporter activity GO:0015111 IMP     iodide transmembrane transporter activity GO:0015111 ISS     iodide transmembrane transporter activity GO:0015111 TAS     monoatomic anion:sodium symporter activity GO:0015373 IDA     protein homodimerization activity GO:0042803 IDA Biological Process     thyroid hormone generation GO:0006590 TAS     monoatomic ion transport GO:0006811 TAS     sodium ion transport GO:0006814 IBA     iodide transport GO:0015705 IMP     sodium ion transmembrane transport GO:0035725 IEA     cellular response to cAMP GO:0071320 IEP     cellular response to gonadotropin stimulus GO:0071371 IEP     transport across blood-brain barrier GO:0150104 NAS     iodide transmembrane transport GO:1904200 IBA     iodide transmembrane transport GO:1904200 IDA     iodide transmembrane transport GO:1904200 IMP     iodide transmembrane transport GO:1904200 ISS     cellular response to forskolin GO:1904322 IDA     cellular response to Thyroid stimulating hormone GO:1904401 IDA Subcellular Localization     nucleus GO:0005634 IDA     cytoplasm GO:0005737 IDA     plasma membrane GO:0005886 IC     plasma membrane GO:0005886 IC     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IMP     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     membrane GO:0016020 TAS     extracellular exosome GO:0070062 HDA     extracellular vesicle GO:1903561 HDA