Gene description for Oxct1
Gene name 3-oxoacid CoA transferase 1
Gene symbol Oxct1
Other names/aliases 2610008O03Rik
Oxct
Oxct2a
Scot-s
Species Mus musculus
 Database cross references - Oxct1
ExoCarta ExoCarta_67041
Vesiclepedia VP_67041
Entrez Gene 67041
UniProt Q9D0K2  
 Oxct1 identified in sEVs derived from the following tissue/cell type
Fibroblasts 23260141    
 Gene ontology annotations for Oxct1
Molecular Function
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 IBA
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 IDA
    succinyl-CoA:3-oxo-acid CoA-transferase activity GO:0008260 ISO
    identical protein binding GO:0042802 ISO
Biological Process
    positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 ISO
    ketone catabolic process GO:0042182 IMP
    ketone body catabolic process GO:0046952 IMP
    ketone body metabolic process GO:1902224 IBA
    ketone body metabolic process GO:1902224 IDA
    ketone body metabolic process GO:1902224 ISO
Subcellular Localization
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IBA
    mitochondrion GO:0005739 ISO
 Experiment description of studies that identified Oxct1 in sEVs
1
Experiment ID 210
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23260141    
Organism Mus musculus
Experiment description Exosomes Mediate Stromal Mobilization of Autocrine Wnt-PCP Signaling in Breast Cancer Cell Migration.
Authors "Luga V, Zhang L, Viloria-Petit AM, Ogunjimi AA, Inanlou MR, Chiu E, Buchanan M, Hosein AN, Basik M, Wrana JL."
Journal name Cell
Publication year 2012
Sample Fibroblasts
Sample name Normal-Fibroblasts (L cells)
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Oxct1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Csl  
Cross-Linking-MS (XL-MS) Mus musculus
2 Atxn1  
Affinity Capture-MS Mus musculus
3 Atp5a1 11946
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
4 Oxct1 67041
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
Cross-Linking-MS (XL-MS) Mus musculus
5 Mapt  
Affinity Capture-MS Mus musculus
6 Ssbp1  
Cross-Linking-MS (XL-MS) Mus musculus
7 Mdh2 17448
Cross-Linking-MS (XL-MS) Mus musculus
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here