Gene description for TP53BP1
Gene name tumor protein p53 binding protein 1
Gene symbol TP53BP1
Other names/aliases 53BP1
p202
p53BP1
Species Homo sapiens
 Database cross references - TP53BP1
ExoCarta ExoCarta_7158
Vesiclepedia VP_7158
Entrez Gene 7158
HGNC 11999
MIM 605230
UniProt Q12888  
 TP53BP1 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for TP53BP1
Molecular Function
    p53 binding GO:0002039 IPI
    damaged DNA binding GO:0003684 IEA
    transcription coregulator activity GO:0003712 IMP
    protein binding GO:0005515 IPI
    methylated histone binding GO:0035064 IDA
    telomeric DNA binding GO:0042162 IEA
    histone binding GO:0042393 IBA
    RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI
    ubiquitin-modified histone reader activity GO:0061649 IDA
    histone reader activity GO:0140566 IDA
Biological Process
    DNA damage checkpoint signaling GO:0000077 IBA
    double-strand break repair via nonhomologous end joining GO:0006303 IDA
    chromatin organization GO:0006325 IEA
    DNA damage response GO:0006974 IDA
    DNA damage response GO:0006974 IDA
    positive regulation of isotype switching GO:0045830 IDA
    positive regulation of isotype switching GO:0045830 IMP
    positive regulation of DNA-templated transcription GO:0045893 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    positive regulation of DNA-binding transcription factor activity GO:0051091 IC
    protein homooligomerization GO:0051260 IDA
    cellular response to X-ray GO:0071481 IEA
    double-strand break repair via classical nonhomologous end joining GO:0097680 IDA
    protein localization to site of double-strand break GO:1990166 IDA
    negative regulation of double-strand break repair via homologous recombination GO:2000042 IDA
Subcellular Localization
    kinetochore GO:0000776 IEA
    chromosome, telomeric region GO:0000781 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    replication fork GO:0005657 IEA
    cytoplasm GO:0005737 IDA
    nuclear body GO:0016604 IDA
    site of double-strand break GO:0035861 IDA
    site of double-strand break GO:0035861 IDA
    DNA repair complex GO:1990391 IEA
 Experiment description of studies that identified TP53BP1 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
10
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
11
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
14
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
18
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
21
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for TP53BP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 SLFN11 91607
Affinity Capture-MS Homo sapiens
3 LIG4 3981
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
4 NPEPPS 9520
Negative Genetic Homo sapiens
5 SLIT2 9353
Affinity Capture-MS Homo sapiens
6 HDAC4  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
7 KPNA3 3839
Affinity Capture-MS Homo sapiens
8 IGSF3 3321
Negative Genetic Homo sapiens
9 BCKDK 10295
Affinity Capture-MS Homo sapiens
10 PAXIP1  
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
11 RBL2 5934
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
12 KPNA1 3836
Affinity Capture-MS Homo sapiens
13 USPL1  
Negative Genetic Homo sapiens
14 HIST1H4A 8359
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
15 MCM9 254394
Negative Genetic Homo sapiens
16 KIAA2013 90231
Negative Genetic Homo sapiens
17 RPA2 6118
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
18 PRPF38A 84950
Affinity Capture-MS Homo sapiens
19 ANAPC5 51433
Affinity Capture-MS Homo sapiens
20 E2F1 1869
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
21 SUB1 10923
Co-fractionation Homo sapiens
22 ACTC1 70
Proximity Label-MS Homo sapiens
23 PAICS 10606
Affinity Capture-MS Homo sapiens
24 BRCA1 672
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
25 CDC23 8697
Affinity Capture-MS Homo sapiens
26 PTPN9 5780
Affinity Capture-MS Homo sapiens
27 UBC 7316
Affinity Capture-Western Homo sapiens
28 ATM 472
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Biochemical Activity Homo sapiens
Co-localization Homo sapiens
29 CHEK2  
Affinity Capture-Western Homo sapiens
30 FHOD1 29109
Negative Genetic Homo sapiens
31 DNAJB6 10049
Proximity Label-MS Homo sapiens
32 APEX1 328
Negative Genetic Homo sapiens
33 TMA16  
Affinity Capture-MS Homo sapiens
34 DPPA4  
Affinity Capture-MS Homo sapiens
35 CAPZB 832
Affinity Capture-MS Homo sapiens
36 Cenpf  
Affinity Capture-MS Mus musculus
37 PCNT  
Two-hybrid Homo sapiens
38 ACR  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
39 SDHB 6390
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
40 CHP1 11261
Negative Genetic Homo sapiens
41 NPLOC4 55666
Affinity Capture-Western Homo sapiens
42 H2afx 15270
Co-localization Mus musculus
43 RNF8  
Co-localization Homo sapiens
44 SPAG9 9043
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
45 KDM2A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
46 COPS5 10987
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
47 MEF2A  
Proximity Label-MS Homo sapiens
48 CUX1 1523
Affinity Capture-MS Homo sapiens
49 MDC1  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Co-localization Homo sapiens
50 MID1IP1  
Negative Genetic Homo sapiens
51 POU5F1  
Affinity Capture-MS Homo sapiens
52 TYRO3 7301
Negative Genetic Homo sapiens
53 NCOA3  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
54 DYNLL1 8655
Two-hybrid Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 SUN2 25777
Affinity Capture-MS Homo sapiens
56 THAP10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
57 EED  
Affinity Capture-MS Homo sapiens
58 DNAJC7 7266
Affinity Capture-MS Homo sapiens
59 CDK1 983
Biochemical Activity Homo sapiens
60 NGLY1 55768
Negative Genetic Homo sapiens
61 RMI2  
Negative Genetic Homo sapiens
62 MRPS7 51081
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 SETD1A 9739
Affinity Capture-MS Homo sapiens
64 SAPCD2  
Negative Genetic Homo sapiens
65 NUDT16L1 84309
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 MTA2 9219
Affinity Capture-MS Homo sapiens
67 SLC25A33  
Negative Genetic Homo sapiens
68 CLASP2 23122
Affinity Capture-MS Homo sapiens
69 MAPK1 5594
Affinity Capture-MS Homo sapiens
70 MCM6 4175
Affinity Capture-MS Homo sapiens
71 SETD8  
Co-localization Homo sapiens
72 UGGT1 56886
Affinity Capture-MS Homo sapiens
73 TOLLIP 54472
Proximity Label-MS Homo sapiens
74 MAPK3 5595
Affinity Capture-MS Homo sapiens
75 PPP5C 5536
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
76 SMC6  
Affinity Capture-MS Homo sapiens
77 UBE2T  
Negative Genetic Homo sapiens
78 CAPZA1 829
Affinity Capture-MS Homo sapiens
79 PELO 53918
Affinity Capture-MS Homo sapiens
80 RB1CC1 9821
Affinity Capture-MS Homo sapiens
81 FOXK1 221937
Affinity Capture-MS Homo sapiens
82 PIAS4  
Co-localization Homo sapiens
83 MCPH1  
Co-localization Homo sapiens
84 BLM 641
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
85 MGA  
Negative Genetic Homo sapiens
86 NBN 4683
Co-localization Homo sapiens
Co-fractionation Homo sapiens
87 UBE2I 7329
Co-localization Homo sapiens
88 EXOC4 60412
Affinity Capture-Western Homo sapiens
89 CBX3 11335
Affinity Capture-MS Homo sapiens
90 TFDP1  
Reconstituted Complex Homo sapiens
91 CHMP6 79643
Negative Genetic Homo sapiens
92 KDM1A 23028
Reconstituted Complex Homo sapiens
93 NUDC 10726
Affinity Capture-MS Homo sapiens
94 VCP 7415
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
95 RNF168  
Co-localization Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
96 DPF2  
Affinity Capture-MS Homo sapiens
97 FOXK2  
Affinity Capture-MS Homo sapiens
98 UBE2L3 7332
Affinity Capture-Western Homo sapiens
99 CDKN3 1033
Affinity Capture-MS Homo sapiens
100 U2AF2 11338
Co-fractionation Homo sapiens
101 RAD18  
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
102 CHEK1  
Co-localization Homo sapiens
103 SUMO2 6613
Reconstituted Complex Homo sapiens
104 POLQ  
Negative Genetic Homo sapiens
105 MEOX2  
Two-hybrid Homo sapiens
106 KPNB1 3837
Affinity Capture-MS Homo sapiens
107 ENO1 2023
Affinity Capture-RNA Homo sapiens
108 CSNK1E 1454
Affinity Capture-MS Homo sapiens
109 ANAPC4 29945
Affinity Capture-MS Homo sapiens
110 DYNLL2 140735
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
111 CDC27 996
Affinity Capture-MS Homo sapiens
112 BIRC5  
Negative Genetic Homo sapiens
113 MYL12A 10627
Affinity Capture-MS Homo sapiens
114 CEBPA  
Protein-peptide Homo sapiens
115 USP28 57646
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
116 FMO1  
Negative Genetic Homo sapiens
117 METTL1 4234
Affinity Capture-MS Homo sapiens
118 ALX3  
Negative Genetic Homo sapiens
119 CCNT1  
Co-fractionation Homo sapiens
120 CACYBP 27101
Affinity Capture-MS Homo sapiens
121 ANAPC7 51434
Affinity Capture-MS Homo sapiens
122 RBL1  
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
123 SPPL3  
Negative Genetic Homo sapiens
124 NUMA1 4926
Affinity Capture-MS Homo sapiens
125 MAGEB18  
Negative Genetic Homo sapiens
126 TMPO 7112
Affinity Capture-MS Homo sapiens
127 HIST1H3A 8350
Co-crystal Structure Homo sapiens
128 FANCD2  
Negative Genetic Homo sapiens
129 NOL8  
Negative Genetic Homo sapiens
130 YWHAZ 7534
Affinity Capture-MS Homo sapiens
131 SMARCD1 6602
Affinity Capture-MS Homo sapiens
132 TYMS 7298
Negative Genetic Homo sapiens
133 SIRT7  
Affinity Capture-MS Homo sapiens
134 ANAPC10  
Affinity Capture-MS Homo sapiens
135 PSMD8 5714
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
136 Trp53  
Two-hybrid Mus musculus
137 SRSF1 6426
Affinity Capture-MS Homo sapiens
138 RFC2 5982
Affinity Capture-MS Homo sapiens
139 DEK 7913
Affinity Capture-MS Homo sapiens
140 PTEN 5728
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
141 SPRR2E  
Affinity Capture-MS Homo sapiens
142 SLC7A5 8140
Negative Genetic Homo sapiens
143 PLK1 5347
Biochemical Activity Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
144 MORF4L1  
Negative Genetic Homo sapiens
145 TP73  
Affinity Capture-MS Homo sapiens
146 SLC35D1  
Negative Genetic Homo sapiens
147 Paxip1  
Affinity Capture-MS Mus musculus
148 NXF1 10482
Affinity Capture-RNA Homo sapiens
149 STRAP 11171
Affinity Capture-MS Homo sapiens
150 ANAPC16  
Affinity Capture-MS Homo sapiens
151 PIP4K2A 5305
Affinity Capture-MS Homo sapiens
152 ACTR5 79913
Negative Genetic Homo sapiens
153 ARID3A  
Affinity Capture-MS Homo sapiens
154 RPA3 6119
Proximity Label-MS Homo sapiens
155 TSEN34 79042
Negative Genetic Homo sapiens
156 MSL1 339287
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
157 PHF6  
Affinity Capture-MS Homo sapiens
158 DHRS7B 25979
Affinity Capture-MS Homo sapiens
159 NFKB1 4790
Affinity Capture-Western Homo sapiens
160 PSMC5 5705
Affinity Capture-MS Homo sapiens
161 GALNTL5  
Two-hybrid Homo sapiens
162 PCGF1 84759
Affinity Capture-MS Homo sapiens
163 Dynll1 56455
Affinity Capture-MS Mus musculus
164 BEND3  
Affinity Capture-MS Homo sapiens
165 TRIM28 10155
Affinity Capture-Western Homo sapiens
166 TP53I3  
Co-localization Homo sapiens
167 LRCH2  
Negative Genetic Homo sapiens
168 HAT1 8520
Affinity Capture-MS Homo sapiens
169 NANOG  
Affinity Capture-MS Homo sapiens
170 HIST1H1T 3010
Affinity Capture-MS Homo sapiens
171 NFATC2  
Affinity Capture-MS Homo sapiens
172 XRCC5 7520
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
173 ARAP1 116985
Two-hybrid Homo sapiens
174 H2AFX 3014
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Co-localization Homo sapiens
Protein-peptide Homo sapiens
Co-localization Homo sapiens
Co-localization Homo sapiens
Co-localization Homo sapiens
175 HIST2H4A 8370
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
176 Scai 320271
Affinity Capture-MS Mus musculus
177 FASN 2194
Affinity Capture-MS Homo sapiens
178 SPOP  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
179 MAPKAP1 79109
Negative Genetic Homo sapiens
180 SIRT6  
Affinity Capture-MS Homo sapiens
181 PARP1 142
Proximity Label-MS Homo sapiens
182 TRPS1  
Affinity Capture-MS Homo sapiens
183 TP53 7157
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
184 RPS21 6227
Affinity Capture-MS Homo sapiens
185 MED4 29079
Negative Genetic Homo sapiens
186 PCMT1 5110
Affinity Capture-MS Homo sapiens
187 Kpna2 16647
Co-crystal Structure Mus musculus
Reconstituted Complex Mus musculus
188 POLR1C 9533
Co-fractionation Homo sapiens
189 RPA1 6117
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
190 MEN1 4221
Affinity Capture-MS Homo sapiens
191 USP1 7398
Negative Genetic Homo sapiens
192 ACAA2 10449
Co-fractionation Homo sapiens
193 SAFB 6294
Affinity Capture-MS Homo sapiens
194 ANAPC1 64682
Affinity Capture-MS Homo sapiens
195 KBTBD6  
Negative Genetic Homo sapiens
196 ZBTB10 65986
Affinity Capture-MS Homo sapiens
197 SHMT2 6472
Affinity Capture-RNA Homo sapiens
198 VAC14 55697
Two-hybrid Homo sapiens
199 KIFAP3 22920
Co-localization Homo sapiens
200 DDX58 23586
Affinity Capture-RNA Homo sapiens
201 NEK1  
Two-hybrid Homo sapiens
202 FLCN 201163
Affinity Capture-MS Homo sapiens
203 ANAPC2 29882
Affinity Capture-MS Homo sapiens
204 NUP50 10762
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
205 NUP107 57122
Co-fractionation Homo sapiens
206 E2F4  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
207 LRPAP1 4043
Affinity Capture-MS Homo sapiens
208 MOV10 4343
Affinity Capture-RNA Homo sapiens
209 RNF20 56254
Negative Genetic Homo sapiens
210 DCLRE1A  
Affinity Capture-Western Homo sapiens
211 FLNA 2316
Affinity Capture-MS Homo sapiens
212 ATP1A1 476
Negative Genetic Homo sapiens
213 CDC16 8881
Affinity Capture-MS Homo sapiens
214 XRCC6 2547
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
215 SIRT3  
Co-localization Homo sapiens
216 GNB2L1 10399
Affinity Capture-MS Homo sapiens
217 AAMP 14
Affinity Capture-MS Homo sapiens
218 RCOR1  
Affinity Capture-MS Homo sapiens
219 EP300 2033
Affinity Capture-MS Homo sapiens
220 IKBKG 8517
Negative Genetic Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here