Gene description for ADCY1
Gene name	adenylate cyclase 1 (brain)
Gene symbol	ADCY1
Other names/aliases	AC1 DFNB44
Species	Homo sapiens
Database cross references - ADCY1
ExoCarta	ExoCarta_107
Vesiclepedia	VP_107
Entrez Gene	107
HGNC	232
MIM	103072
UniProt	Q08828
ADCY1 identified in sEVs derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for ADCY1

Molecular Function     adenylate cyclase activity GO:0004016 IBA     calmodulin binding GO:0005516 IEA     ATP binding GO:0005524 IEA     calcium- and calmodulin-responsive adenylate cyclase activity GO:0008294 ISS     calcium- and calmodulin-responsive adenylate cyclase activity GO:0008294 NAS     metal ion binding GO:0046872 IEA Biological Process     cAMP biosynthetic process GO:0006171 IBA     cAMP biosynthetic process GO:0006171 ISS     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 IBA     adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0007189 ISS     axonogenesis GO:0007409 IEA     long-term memory GO:0007616 IEA     circadian rhythm GO:0007623 IEA     response to xenobiotic stimulus GO:0009410 IEA     positive regulation of CREB transcription factor activity GO:0032793 ISS     intracellular signal transduction GO:0035556 IEA     regulation of circadian rhythm GO:0042752 ISS     cellular response to calcium ion GO:0071277 ISS     presynaptic modulation of chemical synaptic transmission GO:0099171 IEA     neuroinflammatory response GO:0150076 ISS     positive regulation of long-term synaptic potentiation GO:1900273 ISS     cellular response to forskolin GO:1904322 ISS Subcellular Localization     cytoplasm GO:0005737 ISS     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISS     plasma membrane GO:0005886 TAS     membrane raft GO:0045121 IEA     extracellular exosome GO:0070062 HDA     Schaffer collateral - CA1 synapse GO:0098685 IEA     hippocampal mossy fiber to CA3 synapse GO:0098686 IEA     presynapse GO:0098793 IEA     postsynaptic density membrane GO:0098839 IEA     glutamatergic synapse GO:0098978 IEA