Gene description for UTS2
Gene name urotensin 2
Gene symbol UTS2
Other names/aliases PRO1068
U-II
UCN2
UII
Species Homo sapiens
 Database cross references - UTS2
ExoCarta ExoCarta_10911
Vesiclepedia VP_10911
Entrez Gene 10911
HGNC 12636
MIM 604097
UniProt O95399  
 UTS2 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for UTS2
Molecular Function
    signaling receptor binding GO:0005102 TAS
    hormone activity GO:0005179 IEA
Biological Process
    muscle contraction GO:0006936 TAS
    signal transduction GO:0007165 IEA
    chemical synaptic transmission GO:0007268 TAS
    regulation of blood pressure GO:0008217 IBA
    blood vessel diameter maintenance GO:0097746 IEA
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 IBA
    synapse GO:0045202 IEA
 Experiment description of studies that identified UTS2 in sEVs
1
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for UTS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ANLN 54443
Affinity Capture-MS Homo sapiens
2 AURKB 9212
Affinity Capture-MS Homo sapiens
3 Uts2r  
Reconstituted Complex Rattus norvegicus
4 ANTXR1 84168
Affinity Capture-MS Homo sapiens
5 KIF23 9493
Affinity Capture-MS Homo sapiens
6 OTUB1 55611
Affinity Capture-MS Homo sapiens
7 EP300 2033
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



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