Gene description for Arf3
Gene name ADP-ribosylation factor 3
Gene symbol Arf3
Other names/aliases 5430400P17Rik
AI854770
Species Mus musculus
 Database cross references - Arf3
ExoCarta ExoCarta_11842
Vesiclepedia VP_11842
Entrez Gene 11842
UniProt P61205  
 Arf3 identified in sEVs derived from the following tissue/cell type
Mov neuroglial cells 15210972    
 Gene ontology annotations for Arf3
Molecular Function
    GTPase activity GO:0003924 IEA
    GTP binding GO:0005525 IBA
    GTP binding GO:0005525 TAS
Biological Process
    intracellular protein transport GO:0006886 IBA
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 IEA
    retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum GO:0006890 ISO
    protein transport GO:0015031 TAS
    vesicle-mediated transport GO:0016192 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    Golgi apparatus GO:0005794 IDA
    plasma membrane GO:0005886 IBA
    perinuclear region of cytoplasm GO:0048471 IEA
 Experiment description of studies that identified Arf3 in sEVs
1
Experiment ID 39
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|HSC70|FLOT1
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15210972    
Organism Mus musculus
Experiment description Cells release prions in association with exosomes.
Authors "Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, Laude H, Raposo G"
Journal name PNAS
Publication year 2004
Sample Mov neuroglial cells
Sample name Mov neuroglial cell
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QSTAR]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Arf3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Syngap1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
2 Sstr3  
Proximity Label-MS Mus musculus
3 Fmr1  
Affinity Capture-MS Mus musculus
4 Cyfip1 20430
Affinity Capture-MS Mus musculus
5 Eed  
Affinity Capture-MS Mus musculus
6 Arfgap2  
Co-fractionation Mus musculus
7 MAPT  
Reconstituted Complex Homo sapiens
8 Dlg4  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
9 Shank3  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
10 Arfgap1  
Co-fractionation Mus musculus
11 Copb1 70349
Co-fractionation Mus musculus
12 Dlgap1  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
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