Gene description for FAM186A
Gene name family with sequence similarity 186, member A
Gene symbol FAM186A
Other names/aliases -
Species Homo sapiens
 Database cross references - FAM186A
ExoCarta ExoCarta_121006
Vesiclepedia VP_121006
Entrez Gene 121006
HGNC 26980
UniProt A6NE01  
 FAM186A identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for FAM186A
 Experiment description of studies that identified FAM186A in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for FAM186A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 C1QBP 708
Cross-Linking-MS (XL-MS) Homo sapiens
2 ANLN 54443
Affinity Capture-MS Homo sapiens
3 HSPE1 3336
Cross-Linking-MS (XL-MS) Homo sapiens
4 ENO1 2023
Cross-Linking-MS (XL-MS) Homo sapiens
5 EGFR 1956
Affinity Capture-MS Homo sapiens
6 NOLC1 9221
Cross-Linking-MS (XL-MS) Homo sapiens
7 ATP5I 521
Cross-Linking-MS (XL-MS) Homo sapiens
8 PLA2G4D  
Cross-Linking-MS (XL-MS) Homo sapiens
View the network image/svg+xml
 Pathways in which FAM186A is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here