Gene description for CR2
Gene name	complement component (3d/Epstein Barr virus) receptor 2
Gene symbol	CR2
Other names/aliases	C3DR CD21 CR CVID7 SLEB9
Species	Homo sapiens
Database cross references - CR2
ExoCarta	ExoCarta_1380
Vesiclepedia	VP_1380
Entrez Gene	1380
HGNC	2336
MIM	120650
UniProt	P20023
CR2 identified in sEVs derived from the following tissue/cell type
B cells	20458337
B cells	20458337

Gene ontology annotations for CR2

Molecular Function     virus receptor activity GO:0001618 NAS     complement binding GO:0001848 IDA     DNA binding GO:0003677 IDA     complement receptor activity GO:0004875 NAS     transmembrane signaling receptor activity GO:0004888 IDA     transmembrane signaling receptor activity GO:0004888 NAS     protein binding GO:0005515 IPI     immunoglobulin receptor binding GO:0034987 IDA     protein homodimerization activity GO:0042803 IDA Biological Process     complement receptor mediated signaling pathway GO:0002430 IEA     T cell mediated immunity GO:0002456 IBA     immune response GO:0006955 NAS     complement activation, alternative pathway GO:0006957 IMP     complement activation, classical pathway GO:0006958 IEA     B cell differentiation GO:0030183 IDA     B cell proliferation GO:0042100 IDA     B cell activation GO:0042113 IDA     negative regulation of complement activation, classical pathway GO:0045959 IBA     symbiont entry into host cell GO:0046718 IDA     type I interferon-mediated signaling pathway GO:0060337 IDA Subcellular Localization     extracellular space GO:0005615 IBA     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 TAS     membrane GO:0016020 NAS     receptor complex GO:0043235 IDA     extracellular exosome GO:0070062 HDA