Gene description for CTBS
Gene name chitobiase, di-N-acetyl-
Gene symbol CTBS
Other names/aliases CTB
Species Homo sapiens
 Database cross references - CTBS
ExoCarta ExoCarta_1486
Vesiclepedia VP_1486
Entrez Gene 1486
HGNC 2496
MIM 600873
UniProt Q01459  
 CTBS identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for CTBS
Molecular Function
    chitinase activity GO:0004568 IBA
    chitin binding GO:0008061 IEA
Biological Process
    chitin catabolic process GO:0006032 IBA
    oligosaccharide catabolic process GO:0009313 IBA
Subcellular Localization
    extracellular space GO:0005615 HDA
    lysosome GO:0005764 IEA
 Experiment description of studies that identified CTBS in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CTBS
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MARVELD2 153562
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 LILRA5  
Affinity Capture-MS Homo sapiens
3 DEFA1 1667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 NDP  
Affinity Capture-MS Homo sapiens
5 TMEM25  
Affinity Capture-MS Homo sapiens
6 DEFB110  
Affinity Capture-MS Homo sapiens
7 PRG2  
Affinity Capture-MS Homo sapiens
8 PCP4  
Affinity Capture-MS Homo sapiens
9 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
10 IGF2R 3482
Affinity Capture-MS Homo sapiens
11 PTDSS1 9791
Affinity Capture-MS Homo sapiens
12 FBXO6 26270
Affinity Capture-MS Homo sapiens
13 ST7  
Affinity Capture-MS Homo sapiens
14 DDX58 23586
Affinity Capture-RNA Homo sapiens
15 ELSPBP1  
Affinity Capture-MS Homo sapiens
16 DEFB136  
Affinity Capture-MS Homo sapiens
17 CMA1  
Affinity Capture-MS Homo sapiens
18 BTLA  
Affinity Capture-MS Homo sapiens
19 IDS  
Affinity Capture-MS Homo sapiens
20 FBXO2 26232
Affinity Capture-MS Homo sapiens
21 RELB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
22 DEFB135  
Affinity Capture-MS Homo sapiens
23 DEFB123  
Affinity Capture-MS Homo sapiens
24 EDN3  
Affinity Capture-MS Homo sapiens
25 NXPH3  
Affinity Capture-MS Homo sapiens
26 PATE1  
Affinity Capture-MS Homo sapiens
27 FBXW8 26259
Affinity Capture-MS Homo sapiens
28 TMPRSS5  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CTBS is involved
No pathways found





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