Gene description for Myef2
Gene name myelin basic protein expression factor 2, repressor
Gene symbol Myef2
Other names/aliases 9430071B01
mKIAA1341
Species Mus musculus
 Database cross references - Myef2
ExoCarta ExoCarta_17876
Vesiclepedia VP_17876
Entrez Gene 17876
UniProt Q8C854  
 Myef2 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Myef2
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IDA
    DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0001227 IDA
    RNA binding GO:0003723 IEA
    mRNA binding GO:0003729 IBA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IEA
    nucleus GO:0005634 ISO
    cytoplasm GO:0005737 IBA
    ribonucleoprotein complex GO:1990904 IBA
 Experiment description of studies that identified Myef2 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Myef2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Zbtb7b  
Affinity Capture-MS Mus musculus
2 Twist1  
Proximity Label-MS Mus musculus
3 Fxr1 14359
Affinity Capture-MS Mus musculus
4 Elf5  
Affinity Capture-MS Mus musculus
5 Hnrnpm 76936
Co-fractionation Mus musculus
6 Foxp3  
Affinity Capture-MS Mus musculus
7 Eed  
Affinity Capture-MS Mus musculus
8 Mycbp2 105689
Affinity Capture-MS Mus musculus
9 Tada2a  
Co-fractionation Mus musculus
10 Atg16l1  
Affinity Capture-MS Mus musculus
11 Nanog  
Affinity Capture-MS Mus musculus
12 Fancd2  
Affinity Capture-MS Mus musculus
13 Kctd13  
Affinity Capture-MS Mus musculus
14 Smarca4  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Myef2 is involved
No pathways found





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