Gene description for Snrpc
Gene name U1 small nuclear ribonucleoprotein C
Gene symbol Snrpc
Other names/aliases Snrp1c
U1-C
U1C
Species Mus musculus
 Database cross references - Snrpc
ExoCarta ExoCarta_20630
Vesiclepedia VP_20630
Entrez Gene 20630
UniProt Q62241  
 Snrpc identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Snrpc
Molecular Function
    single-stranded RNA binding GO:0003727 ISO
    mRNA binding GO:0003729 IEA
    zinc ion binding GO:0008270 IEA
    zinc ion binding GO:0008270 ISO
    U1 snRNA binding GO:0030619 IEA
    pre-mRNA 5'-splice site binding GO:0030627 IBA
    protein homodimerization activity GO:0042803 ISO
    U1 snRNP binding GO:1990446 ISO
Biological Process
    spliceosomal snRNP assembly GO:0000387 IEA
    spliceosomal snRNP assembly GO:0000387 ISO
    mRNA 5'-splice site recognition GO:0000395 IBA
    mRNA 5'-splice site recognition GO:0000395 IEA
    mRNA splicing, via spliceosome GO:0000398 ISO
Subcellular Localization
    commitment complex GO:0000243 IEA
    nucleoplasm GO:0005654 ISO
    spliceosomal complex GO:0005681 ISO
    U1 snRNP GO:0005685 IBA
    U1 snRNP GO:0005685 ISO
    U1 snRNP GO:0005685 ISS
    Cajal body GO:0015030 ISO
    U2-type prespliceosome GO:0071004 IEA
 Experiment description of studies that identified Snrpc in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Snrpc
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Srsf7 225027
Co-fractionation Mus musculus
2 Mov10 17454
Co-fractionation Mus musculus
3 Slu7  
Co-fractionation Mus musculus
4 Elf5  
Affinity Capture-MS Mus musculus
5 Dhx8  
Co-fractionation Mus musculus
6 Prmt5 27374
Biochemical Activity Mus musculus
7 Prpf4b 19134
Co-fractionation Mus musculus
8 Thoc2  
Co-fractionation Mus musculus
9 Snrnp70 20637
Co-fractionation Mus musculus
10 1110037F02Rik 66185
Co-fractionation Mus musculus
11 Ifi202b  
Co-fractionation Mus musculus
12 Atg16l1  
Affinity Capture-MS Mus musculus
13 Spen  
Co-fractionation Mus musculus
14 Cwc22  
Co-fractionation Mus musculus
15 Tfip11  
Co-fractionation Mus musculus
16 Rbm25  
Co-fractionation Mus musculus
17 Cactin  
Co-fractionation Mus musculus
18 Cdk12  
Co-fractionation Mus musculus
19 Smu1  
Co-fractionation Mus musculus
20 Htatsf1  
Co-fractionation Mus musculus
View the network image/svg+xml



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