Experiment description of studies that identified SETD1B in sEVs

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for SETD1B

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ASH2L 9070 Affinity Capture-MS Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 2 MCRS1   Affinity Capture-MS Homo sapiens 3 WDR82 80335 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 4 YEATS2   Affinity Capture-MS Homo sapiens 5 NCOA6   Affinity Capture-MS Homo sapiens 6 Wdr82   Affinity Capture-MS Mus musculus 7 SETD1A 9739 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 8 WDR5 11091 Affinity Capture-Western Homo sapiens Co-crystal Structure Homo sapiens Protein-peptide Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Protein-peptide Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 SIRT6   Affinity Capture-MS Homo sapiens 10 Kif18b   Affinity Capture-MS Mus musculus 11 HIST1H3A 8350 Biochemical Activity Homo sapiens 12 PAXIP1   Affinity Capture-MS Homo sapiens 13 RERE 473 Affinity Capture-MS Homo sapiens 14 HIST2H3C 126961 Biochemical Activity Homo sapiens 15 KANSL1   Affinity Capture-MS Homo sapiens 16 KMT2B   Affinity Capture-MS Homo sapiens 17 CXXC1   Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Co-fractionation Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 BOD1L1 259282 Affinity Capture-MS Homo sapiens 19 MEN1 4221 Affinity Capture-MS Homo sapiens 20 PHF20L1   Affinity Capture-MS Homo sapiens 21 CSRP2BP   Affinity Capture-MS Homo sapiens 22 ZZZ3   Affinity Capture-MS Homo sapiens 23 KANSL3   Affinity Capture-MS Homo sapiens 24 KDM6A   Affinity Capture-MS Homo sapiens 25 KANSL2   Affinity Capture-MS Homo sapiens 26 WBP4   Affinity Capture-MS Homo sapiens 27 BUB3 9184 Affinity Capture-MS Homo sapiens 28 POLR2A 5430 Affinity Capture-Western Homo sapiens 29 PHF20   Affinity Capture-MS Homo sapiens 30 HIST1H3E 8353 Biochemical Activity Homo sapiens 31 PIP4K2A 5305 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 C12orf49   Negative Genetic Homo sapiens 33 RBM26 64062 Affinity Capture-MS Homo sapiens 34 MVD 4597 Affinity Capture-MS Homo sapiens 35 RPA3 6119 Proximity Label-MS Homo sapiens 36 ZNF608   Affinity Capture-MS Homo sapiens 37 CDK9 1025 Co-fractionation Homo sapiens 38 KMT2C 58508 Affinity Capture-MS Homo sapiens 39 DAXX   Affinity Capture-MS Homo sapiens 40 SYNCRIP 10492 Affinity Capture-MS Homo sapiens 41 MBIP   Affinity Capture-MS Homo sapiens 42 LDLR 3949 Positive Genetic Homo sapiens 43 PRMT2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 44 Bod1   Affinity Capture-MS Mus musculus 45 KAT8   Affinity Capture-MS Homo sapiens 46 KMT2D 8085 Affinity Capture-MS Homo sapiens 47 ATN1   Affinity Capture-MS Homo sapiens 48 Cxxc1   Affinity Capture-MS Mus musculus 49 HCFC1 3054 Affinity Capture-MS Homo sapiens 50 RBBP5 5929 Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens Affinity Capture-MS Homo sapiens 51 HCFC2   Affinity Capture-MS Homo sapiens 52 ZC3H3   Affinity Capture-MS Homo sapiens 53 DPY30 84661 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 ZNF609   Affinity Capture-MS Homo sapiens 55 BOD1   Affinity Capture-MS Homo sapiens 56 KMT2A   Affinity Capture-MS Homo sapiens View the network

Pathways in which SETD1B is involved

No pathways found