Gene description for Thrap3
Gene name
thyroid hormone receptor associated protein 3
Gene symbol
Thrap3
Other names/aliases
9330151F09Rik B230333E16Rik Trap150
Species
Mus musculus
Database cross references - Thrap3
ExoCarta
ExoCarta_230753
Vesiclepedia
VP_230753
Entrez Gene
230753
UniProt
Q569Z6
Thrap3 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
Mast cells
17486113
T-cell lymphoma cells
37309723
Gene ontology annotations for Thrap3
Experiment description of studies that identified Thrap3 in sEVs
1
Experiment ID
907
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
15
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
mrna
Identification method
Microarray
PubMed ID
17486113
Organism
Mus musculus Homo sapiens
Experiment description
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors
"Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name
NCB
Publication year
2007
Sample
Mast cells
Sample name
MC9 Bone marrow-derived mast cells HMC-1
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.11-1.21 g/mL
Molecules identified in the study
Protein mRNA miRNA
Methods used in the study
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array
3
Experiment ID
908
MISEV standards
✔
Biophysical techniques
✔
Enriched markers
✔
Negative markers
✔
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Thrap3
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Jarid2
Affinity Capture-MS
Mus musculus
2
Kctd13
Affinity Capture-MS
Mus musculus
3
Fxr1
14359
Affinity Capture-MS
Mus musculus
4
Tnik
Affinity Capture-MS
Mus musculus
5
Nphp4
Affinity Capture-MS
Mus musculus
6
Fmr1
Affinity Capture-MS
Mus musculus
7
Eed
Affinity Capture-MS
Mus musculus
8
Mycbp2
105689
Affinity Capture-MS
Mus musculus
9
Atxn1
Affinity Capture-MS
Mus musculus
10
Fancd2
Affinity Capture-MS
Mus musculus
View the network
image/svg+xml
Pathways in which Thrap3 is involved
No pathways found