Gene description for Agfg2
Gene name ArfGAP with FG repeats 2
Gene symbol Agfg2
Other names/aliases A630095P14Rik
Hrbl
RAB-R
RABR
Species Mus musculus
 Database cross references - Agfg2
ExoCarta ExoCarta_231801
Vesiclepedia VP_231801
Entrez Gene 231801
UniProt Q80WC7  
 Agfg2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Agfg2
Molecular Function
    molecular_function GO:0003674 ND
    GTPase activator activity GO:0005096 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    acrosome assembly GO:0001675 IBA
    spermatid nucleus differentiation GO:0007289 IBA
    biological_process GO:0008150 ND
    intermediate filament organization GO:0045109 IBA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    cytoplasmic vesicle GO:0031410 IBA
 Experiment description of studies that identified Agfg2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Agfg2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITSN1 6453
Two-hybrid Homo sapiens
2 Eps15 13858
Co-fractionation Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
4 Sstr3  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Agfg2 is involved
No pathways found





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