Gene description for Zfp462
Gene name zinc finger protein 462
Gene symbol Zfp462
Other names/aliases 6030417H05
9430078C22Rik
Gt4-2
Zfpip
Species Mus musculus
 Database cross references - Zfp462
ExoCarta ExoCarta_242466
Vesiclepedia VP_242466
Entrez Gene 242466
 Zfp462 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Zfp462
Molecular Function
    DNA binding GO:0003677 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    chromatin organization GO:0006325 IMP
    negative regulation of DNA binding GO:0043392 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Zfp462 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Zfp462
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Cbx1  
Affinity Capture-MS Mus musculus
2 Tnik  
Affinity Capture-MS Mus musculus
3 Esrrb  
Affinity Capture-MS Mus musculus
4 Cbx5  
Affinity Capture-MS Mus musculus
5 Tfe3  
Affinity Capture-MS Mus musculus
6 Pou5f1  
Affinity Capture-MS Mus musculus
7 Nanog  
Affinity Capture-MS Mus musculus
8 Tfcp2l1  
Affinity Capture-MS Mus musculus
9 Cbx3 12417
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Zfp462 is involved
No pathways found





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