Experiment description of studies that identified FAM21C in sEVs

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for FAM21C

Protein Interactor ExoCarta ID Identification method PubMed Species 1 CCDC93 54520 Affinity Capture-Western Homo sapiens 2 ATXN1 6310 Two-hybrid Homo sapiens 3 VPS35 55737 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens 4 SNX27 81609 Affinity Capture-MS Homo sapiens 5 DCTN2 10540 Proximity Label-MS Homo sapiens 6 FAS 355 Proximity Label-MS Homo sapiens 7 PSMC3 5702 Cross-Linking-MS (XL-MS) Homo sapiens 8 HORMAD2   Affinity Capture-MS Homo sapiens 9 LAMTOR1 55004 Proximity Label-MS Homo sapiens 10 KIAA0196 9897 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 11 LAMP3   Proximity Label-MS Homo sapiens 12 RAB5A 5868 Proximity Label-MS Homo sapiens 13 ACTR3 10096 Proximity Label-MS Homo sapiens 14 FKBP15 23307 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens 15 Capza1 12340 Affinity Capture-MS Mus musculus 16 CAPZA1 829 Affinity Capture-MS Homo sapiens Affinity Capture-Western Homo sapiens 17 CAPZA2 830 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 FAM21A 387680 Affinity Capture-MS Homo sapiens 19 LAMP2 3920 Proximity Label-MS Homo sapiens 20 C9orf78 51759 Affinity Capture-MS Homo sapiens 21 HOOK3 84376 Proximity Label-MS Homo sapiens 22 Wash   Affinity Capture-MS Mus musculus 23 SASS6 163786 Proximity Label-MS Homo sapiens 24 VPS29 51699 Affinity Capture-MS Homo sapiens 25 RAB4A 5867 Proximity Label-MS Homo sapiens 26 VPS26A 9559 Affinity Capture-MS Homo sapiens 27 CAPZB 832 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Co-fractionation Homo sapiens Affinity Capture-Western Homo sapiens 28 ING1   Affinity Capture-MS Homo sapiens 29 WASH3P   Affinity Capture-MS Homo sapiens 30 CEP135   Proximity Label-MS Homo sapiens 31 CLTA 1211 Proximity Label-MS Homo sapiens 32 GOLGA1   Proximity Label-MS Homo sapiens 33 RAB7A 7879 Proximity Label-MS Homo sapiens 34 AMOT 154796 Proximity Label-MS Homo sapiens 35 ACTB 60 Proximity Label-MS Homo sapiens 36 CCDC22 28952 Affinity Capture-Western Homo sapiens 37 STIL   Proximity Label-MS Homo sapiens 38 CCDC53 51019 Co-fractionation Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 WASH1 100287171 Co-fractionation Homo sapiens 40 RPA3 6119 Proximity Label-MS Homo sapiens 41 KIAA1033 23325 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Co-fractionation Homo sapiens 42 STX6 10228 Proximity Label-MS Homo sapiens 43 RAB9A 9367 Proximity Label-MS Homo sapiens View the network

Pathways in which FAM21C is involved

No pathways found