Gene description for GABRB3
Gene name	gamma-aminobutyric acid (GABA) A receptor, beta 3
Gene symbol	GABRB3
Other names/aliases	ECA5
Species	Homo sapiens
Database cross references - GABRB3
ExoCarta	ExoCarta_2562
Vesiclepedia	VP_2562
Entrez Gene	2562
HGNC	4083
MIM	137192
UniProt	P28472
GABRB3 identified in sEVs derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Hepatocellular carcinoma cells	26054723

Gene ontology annotations for GABRB3

Molecular Function     GABA-A receptor activity GO:0004890 IBA     GABA-A receptor activity GO:0004890 IDA     GABA-A receptor activity GO:0004890 IMP     GABA-A receptor activity GO:0004890 ISS     chloride channel activity GO:0005254 IBA     GABA-gated chloride ion channel activity GO:0022851 IDA     GABA-gated chloride ion channel activity GO:0022851 IMP     GABA-gated chloride ion channel activity GO:0022851 ISS     identical protein binding GO:0042802 IPI Biological Process     signal transduction GO:0007165 TAS     gamma-aminobutyric acid signaling pathway GO:0007214 IDA     gamma-aminobutyric acid signaling pathway GO:0007214 IMP     gamma-aminobutyric acid signaling pathway GO:0007214 ISS     gamma-aminobutyric acid signaling pathway GO:0007214 NAS     synaptic transmission, GABAergic GO:0051932 IDA     synaptic transmission, GABAergic GO:0051932 NAS     roof of mouth development GO:0060021 ISS     cellular response to histamine GO:0071420 IDA     chloride transmembrane transport GO:1902476 IBA     chloride transmembrane transport GO:1902476 IDA     chloride transmembrane transport GO:1902476 IMP     chloride transmembrane transport GO:1902476 ISS     chloride transmembrane transport GO:1902476 NAS     inhibitory synapse assembly GO:1904862 IDA Subcellular Localization     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 IMP     plasma membrane GO:0005886 TAS     cytoplasmic vesicle membrane GO:0030659 IEA     chloride channel complex GO:0034707 IEA     dendritic spine GO:0043197 IDA     postsynaptic membrane GO:0045211 IDA     postsynaptic specialization membrane GO:0099634 ISS     GABA-A receptor complex GO:1902711 IBA     GABA-A receptor complex GO:1902711 IDA     GABA-A receptor complex GO:1902711 IMP     GABA-A receptor complex GO:1902711 IPI     GABA-A receptor complex GO:1902711 ISS