Gene description for RNU11
Gene name RNA, U11 small nuclear
Gene symbol RNU11
Other names/aliases RNU11-1
U11
Species Homo sapiens
 Database cross references - RNU11
ExoCarta ExoCarta_26824
Vesiclepedia VP_26824
Entrez Gene 26824
HGNC 10108
 RNU11 identified in sEVs derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for RNU11
Molecular Function
    pre-mRNA 5'-splice site binding GO:0030627 IEA
Biological Process
    mRNA 5'-splice site recognition GO:0000395 IEA
Subcellular Localization
    U11 snRNP GO:0005692 IEA
 Experiment description of studies that identified RNU11 in sEVs
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule snRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description "Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting"
Authors "Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar"
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for RNU11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DHX15 1665
Affinity Capture-MS Homo sapiens
2 SF3B2 10992
Affinity Capture-MS Homo sapiens
3 SNRPG 6637
Affinity Capture-MS Homo sapiens
4 TOE1 114034
Affinity Capture-MS Homo sapiens
5 ZCRB1  
Affinity Capture-MS Homo sapiens
6 YBX1 4904
Affinity Capture-MS Homo sapiens
7 SF3B4 10262
Affinity Capture-MS Homo sapiens
8 PRPF6 24148
Affinity Capture-MS Homo sapiens
9 SNRNP35  
Affinity Capture-MS Homo sapiens
10 PRPF8 10594
Affinity Capture-MS Homo sapiens
11 PRKRIP1 79706
Affinity Capture-MS Homo sapiens
12 ZMAT5  
Affinity Capture-MS Homo sapiens
13 SNRNP25  
Affinity Capture-MS Homo sapiens
14 RNPC3  
Affinity Capture-MS Homo sapiens
15 EFTUD2 9343
Affinity Capture-MS Homo sapiens
16 SNRNP200 23020
Affinity Capture-MS Homo sapiens
17 SNRPD1 6632
Affinity Capture-MS Homo sapiens
18 SF3B1 23451
Affinity Capture-MS Homo sapiens
19 PHF5A 84844
Affinity Capture-MS Homo sapiens
20 SF3B3 23450
Affinity Capture-MS Homo sapiens
21 SNRNP48  
Affinity Capture-MS Homo sapiens
22 PDCD7  
Affinity Capture-MS Homo sapiens
23 SNRPD2 6633
Affinity Capture-MS Homo sapiens
24 SNRPD3 6634
Affinity Capture-MS Homo sapiens
25 U2AF1 7307
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RNU11 is involved
No pathways found





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