Gene description for C5orf51
Gene name chromosome 5 open reading frame 51
Gene symbol C5orf51
Other names/aliases -
Species Homo sapiens
 Database cross references - C5orf51
ExoCarta ExoCarta_285636
Vesiclepedia VP_285636
Entrez Gene 285636
HGNC 27750
UniProt A6NDU8  
 C5orf51 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for C5orf51
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mitophagy GO:0000423 IMP
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    cytosol GO:0005829 IDA
 Experiment description of studies that identified C5orf51 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for C5orf51
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FBXW7  
Synthetic Lethality Homo sapiens
2 TACSTD2 4070
Affinity Capture-MS Homo sapiens
3 MRM1  
Affinity Capture-MS Homo sapiens
4 FAM19A3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 HAT1 8520
Co-fractionation Homo sapiens
6 C10orf82  
Affinity Capture-MS Homo sapiens
7 RPA3 6119
Proximity Label-MS Homo sapiens
8 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
9 GPR17 2840
Affinity Capture-MS Homo sapiens
10 RAB7A 7879
Proximity Label-MS Homo sapiens
11 LRFN4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 HCST  
Affinity Capture-MS Homo sapiens
13 SUOX  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which C5orf51 is involved
No pathways found





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