Gene description for ILDR1
Gene name immunoglobulin-like domain containing receptor 1
Gene symbol ILDR1
Other names/aliases DFNB42
ILDR1alpha
ILDR1alpha'
ILDR1beta
Species Homo sapiens
 Database cross references - ILDR1
ExoCarta ExoCarta_286676
Vesiclepedia VP_286676
Entrez Gene 286676
HGNC 28741
MIM 609739
UniProt Q86SU0  
 ILDR1 identified in sEVs derived from the following tissue/cell type
Keratinocytes 19530224    
Keratinocytes 19530224    
 Gene ontology annotations for ILDR1
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IDA
    high-density lipoprotein particle receptor activity GO:0070506 IBA
    high-density lipoprotein particle receptor activity GO:0070506 ISS
Biological Process
    epithelial structure maintenance GO:0010669 ISS
    vesicle-mediated transport GO:0016192 IEA
    peptide hormone secretion GO:0030072 IEA
    regulation of RNA splicing GO:0043484 ISS
    establishment of localization in cell GO:0051649 IEA
    protein localization to tricellular tight junction GO:0061833 ISS
    response to fatty acid GO:0070542 ISS
    positive regulation of peptide hormone secretion GO:0090277 ISS
    tricellular tight junction assembly GO:1904274 ISS
    cellular response to leukemia inhibitory factor GO:1990830 IEA
Subcellular Localization
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    bicellular tight junction GO:0005923 IEA
    protein-containing complex GO:0032991 IDA
    tricellular tight junction GO:0061689 ISS
    tight junction GO:0070160 IDA
 Experiment description of studies that identified ILDR1 in sEVs
1
Experiment ID 189
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Differentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 190
MISEV standards
✔
EM
Biophysical techniques
✔
HSC70
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19530224    
Organism Homo sapiens
Experiment description Profile of exosomes related proteins released by differentiated and undifferentiated human keratinocytes.
Authors "Chavez-Muñoz C, Kilani RT, Ghahary A."
Journal name J Cell Physiol
Publication year 2009
Sample Keratinocytes
Sample name Keratinocytes - Undifferentiated
Isolation/purification methods Differential centrifugation
Filtration
Sucrose cushion
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ILDR1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IDE 3416
Affinity Capture-MS Homo sapiens
2 HECW2  
Affinity Capture-MS Homo sapiens
3 NEDD4 4734
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ITCH 83737
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 HECW1  
Affinity Capture-MS Homo sapiens
6 NEDD4L 23327
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 FBP1 2203
Affinity Capture-MS Homo sapiens
8 WWP1 11059
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 HSPA1A 3303
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ILDR1 is involved
No pathways found





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