Gene description for IGLC7
Gene name immunoglobulin lambda constant 7
Gene symbol IGLC7
Other names/aliases C7
Species Homo sapiens
 Database cross references - IGLC7
ExoCarta ExoCarta_28834
Vesiclepedia VP_28834
Entrez Gene 28834
HGNC 5861
 IGLC7 identified in sEVs derived from the following tissue/cell type
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
 Gene ontology annotations for IGLC7
Molecular Function
    antigen binding GO:0003823 IBA
Biological Process
    adaptive immune response GO:0002250 NAS
    immunoglobulin mediated immune response GO:0016064 IBA
    B cell receptor signaling pathway GO:0050853 NAS
Subcellular Localization
    extracellular region GO:0005576 TAS
    extracellular space GO:0005615 NAS
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    IgG immunoglobulin complex GO:0071735 IBA
    IgG immunoglobulin complex GO:0071735 NAS
    IgD immunoglobulin complex GO:0071738 NAS
    IgE immunoglobulin complex GO:0071742 NAS
    IgA immunoglobulin complex GO:0071745 NAS
    IgM immunoglobulin complex GO:0071753 NAS
 Experiment description of studies that identified IGLC7 in sEVs
1
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
3
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IGLC7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CERS3  
Affinity Capture-MS Homo sapiens
2 IGLL5 100423062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 SSUH2  
Affinity Capture-MS Homo sapiens
4 ITLN2  
Affinity Capture-MS Homo sapiens
5 YWHAQ 10971
Affinity Capture-MS Homo sapiens
6 EGFL8  
Affinity Capture-MS Homo sapiens
7 UBE3A 7337
Affinity Capture-MS Homo sapiens
8 ICE2  
Affinity Capture-MS Homo sapiens
9 BAG1 573
Affinity Capture-MS Homo sapiens
10 FANCD2  
Affinity Capture-MS Homo sapiens
11 RNF115  
Affinity Capture-MS Homo sapiens
12 NRSN1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which IGLC7 is involved
No pathways found





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