Gene description for CG7054
Gene name CG7054 gene product from transcript CG7054-RA
Gene symbol CG7054
Other names/aliases DmelCG7054
Species Drosophila melanogaster
 Database cross references - CG7054
ExoCarta ExoCarta_42643
Vesiclepedia VP_42643
Entrez Gene 42643
 CG7054 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG7054
Biological Process
    negative regulation of ERK1 and ERK2 cascade GO:0070373 ISS
Subcellular Localization
    cytosol GO:0005829 ISS
 Experiment description of studies that identified CG7054 in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG7054
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Su(var)2-10  
Two-hybrid Drosophila melanogaster
2 awd  
Affinity Capture-MS Drosophila melanogaster
3 vnd  
Two-hybrid Drosophila melanogaster
4 Df31  
Affinity Capture-MS Drosophila melanogaster
5 TBCB  
Affinity Capture-MS Drosophila melanogaster
6 CG2004  
Affinity Capture-MS Drosophila melanogaster
7 CG11164  
Two-hybrid Drosophila melanogaster
8 AnxB10  
Affinity Capture-MS Drosophila melanogaster
9 Sh3beta 38820
Affinity Capture-MS Drosophila melanogaster
10 Surf4  
Two-hybrid Drosophila melanogaster
11 CG10638  
Affinity Capture-MS Drosophila melanogaster
12 cas  
Two-hybrid Drosophila melanogaster
13 Not3  
Two-hybrid Drosophila melanogaster
14 Crc  
Affinity Capture-MS Drosophila melanogaster
15 CG11267  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which CG7054 is involved
No pathways found





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