Gene description for TSPAN11
Gene name tetraspanin 11
Gene symbol TSPAN11
Other names/aliases VSSW1971
Species Homo sapiens
 Database cross references - TSPAN11
ExoCarta ExoCarta_441631
Vesiclepedia VP_441631
Entrez Gene 441631
HGNC 30795
UniProt A1L157  
 TSPAN11 identified in sEVs derived from the following tissue/cell type
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
 Gene ontology annotations for TSPAN11
Subcellular Localization
    plasma membrane GO:0005886 IBA
 Experiment description of studies that identified TSPAN11 in sEVs
1
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for TSPAN11
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARL6IP5 10550
Affinity Capture-MS Homo sapiens
2 IGLL5 100423062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 REEP5 7905
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 ITGB1 3688
Affinity Capture-MS Homo sapiens
5 ITGA7 3679
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 TM9SF4 9777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 ITGA6 3655
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 ESYT1 23344
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 POMC  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 NRP2 8828
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 CYB5R3 1727
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TSPAN11 is involved
No pathways found





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