Gene description for MUC7
Gene name mucin 7, secreted
Gene symbol MUC7
Other names/aliases MG2
Species Homo sapiens
 Database cross references - MUC7
ExoCarta ExoCarta_4589
Vesiclepedia VP_4589
Entrez Gene 4589
HGNC 7518
MIM 158375
UniProt Q8TAX7  
 MUC7 identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for MUC7
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    killing of cells of another organism GO:0031640 IDA
    antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA
Subcellular Localization
    Golgi lumen GO:0005796 TAS
    plasma membrane GO:0005886 TAS
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified MUC7 in sEVs
1
Experiment ID 66
MISEV standards
✔
IEM
Biophysical techniques
✔
TSG101|Alix|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for MUC7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 FNDC5  
Affinity Capture-MS Homo sapiens
2 STK11 6794
Affinity Capture-MS Homo sapiens
3 CAMK1D 57118
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 HBQ1  
Affinity Capture-MS Homo sapiens
5 RCAN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 SRRT 51593
Affinity Capture-MS Homo sapiens
7 KIR2DS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 TIMM10  
Affinity Capture-MS Homo sapiens
9 UCP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 NPB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 LTF 4057
Far Western Homo sapiens
12 SELL 6402
Reconstituted Complex Homo sapiens
13 SLIRP 81892
Affinity Capture-MS Homo sapiens
14 JAK2 3717
Affinity Capture-MS Homo sapiens
15 ZNF491  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 FRMD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 SCAMP2 10066
Affinity Capture-MS Homo sapiens
18 GKN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 GALNT14  
Biochemical Activity Homo sapiens
20 CORO1C 23603
Affinity Capture-MS Homo sapiens
21 GTF2B 2959
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
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