Experiment description of studies that identified MYO1A in sEVs

1 Experiment ID 286 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✘ Negative markers ✔ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25890246     Organism Homo sapiens Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct. Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ." Journal name Methods Publication year 2015 Sample Colorectal cancer cells Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2 Isolation/purification methods Differential centrifugation Filtration Sequential centrifugal ultrafiltration Centrifugal concentration Flotation density - Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

2 Experiment ID 224 MISEV standards ✔ Biophysical techniques ✔ Enriched markers ✔ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S" Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for MYO1A

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MYO1C 4641 Cross-Linking-MS (XL-MS) Homo sapiens 2 TFCP2 7024 Affinity Capture-MS Homo sapiens 3 ANLN 54443 Affinity Capture-MS Homo sapiens 4 AURKB 9212 Affinity Capture-MS Homo sapiens 5 FBXO25   Affinity Capture-MS Homo sapiens 6 FOXQ1   Affinity Capture-MS Homo sapiens 7 PLEKHA4 57664 Affinity Capture-MS Homo sapiens 8 KIF1C 10749 Affinity Capture-MS Homo sapiens 9 KIF20A 10112 Affinity Capture-MS Homo sapiens 10 MYO1D 4642 Cross-Linking-MS (XL-MS) Homo sapiens 11 YAP1 10413 Affinity Capture-MS Homo sapiens 12 KIF23 9493 Affinity Capture-MS Homo sapiens 13 KIF14 9928 Affinity Capture-MS Homo sapiens 14 USP20   Affinity Capture-MS Homo sapiens 15 CNN1 1264 Reconstituted Complex Homo sapiens 16 CUL1 8454 Affinity Capture-MS Homo sapiens 17 ECT2 1894 Affinity Capture-MS Homo sapiens View the network

Pathways in which MYO1A is involved

No pathways found