Gene description for OAS2
Gene name	2'-5'-oligoadenylate synthetase 2, 69/71kDa
Gene symbol	OAS2
Other names/aliases	-
Species	Homo sapiens
Database cross references - OAS2
ExoCarta	ExoCarta_4939
Vesiclepedia	VP_4939
Entrez Gene	4939
HGNC	8087
MIM	603350
UniProt	P29728
OAS2 identified in sEVs derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for OAS2

Molecular Function     2'-5'-oligoadenylate synthetase activity GO:0001730 IBA     2'-5'-oligoadenylate synthetase activity GO:0001730 IDA     2'-5'-oligoadenylate synthetase activity GO:0001730 IMP     double-stranded RNA binding GO:0003725 IBA     double-stranded RNA binding GO:0003725 IDA     double-stranded RNA binding GO:0003725 IMP     protein binding GO:0005515 IPI     ATP binding GO:0005524 IMP     metal ion binding GO:0046872 IEA Biological Process     nucleobase-containing compound metabolic process GO:0006139 TAS     RNA catabolic process GO:0006401 IEA     response to virus GO:0009615 TAS     positive regulation of interferon-beta production GO:0032728 IMP     positive regulation of tumor necrosis factor production GO:0032760 IMP     defense response to bacterium GO:0042742 IMP     negative regulation of viral genome replication GO:0045071 IBA     defense response to virus GO:0051607 ISS     type I interferon-mediated signaling pathway GO:0060337 IBA     type I interferon-mediated signaling pathway GO:0060337 ISS     interleukin-27-mediated signaling pathway GO:0070106 IBA     interleukin-27-mediated signaling pathway GO:0070106 IDA     antiviral innate immune response GO:0140374 IBA     regulation of lactation GO:1903487 ISS Subcellular Localization     nucleoplasm GO:0005654 IBA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 IBA     cytosol GO:0005829 TAS     membrane GO:0016020 HDA     membrane GO:0016020 IBA     intracellular membrane-bounded organelle GO:0043231 TAS     perinuclear region of cytoplasm GO:0048471 IDA