Gene description for DACT1
Gene name	dishevelled-binding antagonist of beta-catenin 1
Gene symbol	DACT1
Other names/aliases	DAPPER DAPPER1 DPR1 FRODO HDPR1 THYEX3
Species	Homo sapiens
Database cross references - DACT1
ExoCarta	ExoCarta_51339
Vesiclepedia	VP_51339
Entrez Gene	51339
HGNC	17748
MIM	607861
UniProt	Q9NYF0
DACT1 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells	25944692

Gene ontology annotations for DACT1

Molecular Function     protein kinase C binding GO:0005080 ISS     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 IDA     beta-catenin binding GO:0008013 IPI     histone deacetylase binding GO:0042826 IPI     protein kinase A binding GO:0051018 IDA     RNA polymerase II-specific DNA-binding transcription factor binding GO:0061629 IPI     delta-catenin binding GO:0070097 ISS Biological Process     negative regulation of transcription by RNA polymerase II GO:0000122 IDA     Wnt signaling pathway GO:0016055 IEA     neural tube development GO:0021915 IMP     positive regulation of Wnt signaling pathway GO:0030177 IDA     negative regulation of Wnt signaling pathway GO:0030178 IDA     negative regulation of Wnt signaling pathway GO:0030178 IGI     negative regulation of Wnt signaling pathway GO:0030178 IMP     regulation of protein stability GO:0031647 IDA     negative regulation of protein binding GO:0032091 IGI     positive regulation of protein binding GO:0032092 IGI     positive regulation of protein catabolic process GO:0045732 IDA     positive regulation of protein catabolic process GO:0045732 IDA     positive regulation of protein catabolic process GO:0045732 IMP     negative regulation of JNK cascade GO:0046329 IBA     negative regulation of JNK cascade GO:0046329 IDA     embryonic hindgut morphogenesis GO:0048619 ISS     regulation of canonical Wnt signaling pathway GO:0060828 IMP     negative regulation of canonical Wnt signaling pathway GO:0090090 IBA     negative regulation of canonical Wnt signaling pathway GO:0090090 IGI     negative regulation of canonical Wnt signaling pathway GO:0090090 IMP     positive regulation of canonical Wnt signaling pathway GO:0090263 IMP     regulation of nodal signaling pathway GO:1900107 IDA     negative regulation of beta-catenin-TCF complex assembly GO:1904864 IDA     regulation of Wnt signaling pathway, planar cell polarity pathway GO:2000095 IBA     regulation of Wnt signaling pathway, planar cell polarity pathway GO:2000095 ISS     negative regulation of G1/S transition of mitotic cell cycle GO:2000134 IDA Subcellular Localization     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 IDA     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IDA     cytosol GO:0005829 TAS     beta-catenin destruction complex GO:0030877 IDA     synapse GO:0045202 IEA