Gene description for PDGFRL
Gene name platelet-derived growth factor receptor-like
Gene symbol PDGFRL
Other names/aliases PDGRL
PRLTS
Species Homo sapiens
 Database cross references - PDGFRL
ExoCarta ExoCarta_5157
Vesiclepedia VP_5157
Entrez Gene 5157
HGNC 8805
MIM 604584
UniProt Q15198  
 PDGFRL identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for PDGFRL
Molecular Function
    platelet activating factor receptor activity GO:0004992 TAS
    platelet-derived growth factor beta-receptor activity GO:0005019 TAS
Biological Process
    G protein-coupled receptor signaling pathway GO:0007186 IEA
    platelet-derived growth factor receptor-beta signaling pathway GO:0035791 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
 Experiment description of studies that identified PDGFRL in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for PDGFRL
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 TNFSF8  
Affinity Capture-MS Homo sapiens
2 SIL1 64374
Affinity Capture-MS Homo sapiens
3 CCL3  
Affinity Capture-MS Homo sapiens
4 MOCS1  
Affinity Capture-MS Homo sapiens
5 RCOR1  
Affinity Capture-MS Homo sapiens
6 RCOR2 283248
Affinity Capture-MS Homo sapiens
7 PDGFRA 5156
Affinity Capture-MS Homo sapiens
8 HS3ST1  
Affinity Capture-MS Homo sapiens
9 IKBIP 121457
Affinity Capture-MS Homo sapiens
10 CBLN4  
Affinity Capture-MS Homo sapiens
11 RCOR3  
Affinity Capture-MS Homo sapiens
12 ITIH2 3698
Affinity Capture-MS Homo sapiens
13 SP3  
Affinity Capture-MS Homo sapiens
14 ZMYM2  
Affinity Capture-MS Homo sapiens
15 C1QTNF7  
Affinity Capture-MS Homo sapiens
16 SGSM1  
Affinity Capture-MS Homo sapiens
17 ANKRD28 23243
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which PDGFRL is involved
No pathways found





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