Experiment description of studies that identified CCDC186 in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for CCDC186

Protein Interactor ExoCarta ID Identification method PubMed Species 1 YES1 7525 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 KRT27 342574 Affinity Capture-MS Homo sapiens 3 BAG3 9531 Affinity Capture-Luminescence Homo sapiens 4 Rassf1   Affinity Capture-MS Mus musculus 5 NUP62 23636 Affinity Capture-MS Homo sapiens 6 RUNDC3A   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 LRRC48   Affinity Capture-MS Homo sapiens 8 TSNAXIP1 55815 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 WHAMMP3   Affinity Capture-MS Homo sapiens 10 LAMTOR1 55004 Proximity Label-MS Homo sapiens 11 KRT38 8687 Affinity Capture-MS Homo sapiens 12 PLEKHA5 54477 Two-hybrid Homo sapiens 13 ENTHD2   Affinity Capture-MS Homo sapiens 14 DUSP23 54935 Two-hybrid Homo sapiens 15 Pten   Affinity Capture-MS Mus musculus 16 KRT40   Affinity Capture-MS Homo sapiens 17 SIKE1   Affinity Capture-MS Homo sapiens 18 Ktn1   Affinity Capture-MS Mus musculus 19 RAB27B 5874 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 RABEP1 9135 Affinity Capture-MS Homo sapiens View the network

Pathways in which CCDC186 is involved

No pathways found