Gene description for Hnrnph2
Gene name heterogeneous nuclear ribonucleoprotein H2
Gene symbol Hnrnph2
Other names/aliases DXHXS1271E
Ftp-3
Ftp3
H'
HNRNP
Hnrph2
Species Mus musculus
 Database cross references - Hnrnph2
ExoCarta ExoCarta_56258
Vesiclepedia VP_56258
Entrez Gene 56258
UniProt P70333  
 Hnrnph2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Hnrnph2
Molecular Function
    RNA binding GO:0003723 IBA
    RNA binding GO:0003723 IEA
Biological Process
    regulation of RNA splicing GO:0043484 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 ISO
    nucleoplasm GO:0005654 ISS
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    postsynaptic density GO:0014069 IEA
    postsynaptic density GO:0014069 ISO
    ribonucleoprotein complex GO:1990904 IBA
    ribonucleoprotein complex GO:1990904 ISO
 Experiment description of studies that identified Hnrnph2 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Hnrnph2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Lmna 16905
Affinity Capture-MS Mus musculus
2 Qk  
Co-fractionation Mus musculus
3 SUGP1  
Two-hybrid Homo sapiens
4 GZMB  
Biochemical Activity Homo sapiens
5 Atxn1  
Proximity Label-MS Mus musculus
6 SF1 7536
Two-hybrid Homo sapiens
7 Vcp 269523
Co-fractionation Mus musculus
8 Iqcb1  
Affinity Capture-MS Mus musculus
9 CFL1 1072
Two-hybrid Homo sapiens
10 Mecp2  
Affinity Capture-MS Mus musculus
11 RBM7  
Two-hybrid Homo sapiens
12 Tmem173  
Proximity Label-MS Mus musculus
13 PRR3  
Two-hybrid Homo sapiens
14 MAPT  
Reconstituted Complex Homo sapiens
15 Dmrt2  
Affinity Capture-MS Mus musculus
16 Nanog  
Affinity Capture-MS Mus musculus
17 Npm1 18148
Affinity Capture-MS Mus musculus
18 Eed  
Affinity Capture-MS Mus musculus
19 Usp7  
Affinity Capture-MS Mus musculus
20 TXNL4A 10907
Two-hybrid Homo sapiens
21 BAG4  
Two-hybrid Homo sapiens
22 Fancd2  
Affinity Capture-MS Mus musculus
23 Nono 53610
Two-hybrid Mus musculus
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