Gene description for ANKS1B
Gene name ankyrin repeat and sterile alpha motif domain containing 1B
Gene symbol ANKS1B
Other names/aliases AIDA
AIDA-1
ANKS2
EB-1
EB1
cajalin-2
Species Homo sapiens
 Database cross references - ANKS1B
ExoCarta ExoCarta_56899
Vesiclepedia VP_56899
Entrez Gene 56899
HGNC 24600
MIM 607815
UniProt Q7Z6G8  
 ANKS1B identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for ANKS1B
Molecular Function
    protein binding GO:0005515 IPI
    ephrin receptor binding GO:0046875 IBA
    ephrin receptor binding GO:0046875 IPI
Biological Process
    ephrin receptor signaling pathway GO:0048013 IBA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    centrosome GO:0005813 IDA
    cytosol GO:0005829 IBA
    plasma membrane GO:0005886 IDA
    postsynaptic density GO:0014069 IEA
    Cajal body GO:0015030 IEA
    dendritic spine GO:0043197 IEA
 Experiment description of studies that identified ANKS1B in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for ANKS1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 APP 351
Reconstituted Complex Homo sapiens
2 ERBB4 2066
Protein-peptide Homo sapiens
3 SNRPB 6628
Cross-Linking-MS (XL-MS) Homo sapiens
4 ARHGAP26 23092
Affinity Capture-MS Homo sapiens
5 ANLN 54443
Affinity Capture-MS Homo sapiens
6 EPHA8  
Affinity Capture-Western Homo sapiens
7 LRP1 4035
Two-hybrid Homo sapiens
8 FLNC 2318
Affinity Capture-MS Homo sapiens
9 RIN2  
Affinity Capture-MS Homo sapiens
10 DAB2IP 153090
Affinity Capture-MS Homo sapiens
11 HSF2BP  
Two-hybrid Homo sapiens
12 ERBB2 2064
Protein-peptide Homo sapiens
13 UBC 7316
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
14 EGFR 1956
Protein-peptide Homo sapiens
15 CREBBP  
Two-hybrid Homo sapiens
16 MCC 4163
Affinity Capture-MS Homo sapiens
17 RIN1 9610
Two-hybrid Homo sapiens
18 LRP2 4036
Two-hybrid Homo sapiens
19 RASAL2 9462
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ANKS1B is involved
No pathways found





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