Gene description for ATP10D
Gene name ATPase, class V, type 10D
Gene symbol ATP10D
Other names/aliases ATPVD
Species Homo sapiens
 Database cross references - ATP10D
ExoCarta ExoCarta_57205
Vesiclepedia VP_57205
Entrez Gene 57205
HGNC 13549
UniProt Q9P241  
 ATP10D identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ATP10D
Molecular Function
    magnesium ion binding GO:0000287 NAS
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 NAS
    ATP hydrolysis activity GO:0016887 IEA
    ATPase-coupled intramembrane lipid transporter activity GO:0140326 IBA
    ATPase-coupled intramembrane lipid transporter activity GO:0140326 NAS
    ATPase-coupled intramembrane lipid transporter activity GO:0140326 TAS
    glycosylceramide flippase activity GO:0140351 IDA
Biological Process
    monoatomic cation transport GO:0006812 NAS
    monoatomic ion transmembrane transport GO:0034220 TAS
    phospholipid translocation GO:0045332 IBA
    phospholipid translocation GO:0045332 NAS
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    endoplasmic reticulum GO:0005783 IDA
    endoplasmic reticulum membrane GO:0005789 IEA
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 NAS
    phospholipid-translocating ATPase complex GO:1990531 IDA
    phospholipid-translocating ATPase complex GO:1990531 IPI
 Experiment description of studies that identified ATP10D in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ATP10D
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 VMA21  
Affinity Capture-MS Homo sapiens
2 NXF1 10482
Affinity Capture-RNA Homo sapiens
3 ANLN 54443
Affinity Capture-MS Homo sapiens
4 EPDR1 54749
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ATP10D is involved
PathwayEvidenceSource
Ion channel transport TAS Reactome
Ion transport by P-type ATPases TAS Reactome
Transport of small molecules TAS Reactome





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