Gene description for Gmfb
Gene name glia maturation factor, beta
Gene symbol Gmfb
Other names/aliases 3110001H22Rik
3110001O16Rik
AI851627
C79176
D14Ertd630e
Species Mus musculus
 Database cross references - Gmfb
ExoCarta ExoCarta_63985
Vesiclepedia VP_63985
Entrez Gene 63985
UniProt Q9CQI3  
 Gmfb identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Gmfb
Molecular Function
    actin binding GO:0003779 IEA
    growth factor activity GO:0008083 IEA
    Arp2/3 complex binding GO:0071933 IBA
    Arp2/3 complex binding GO:0071933 IEA
Biological Process
    signal transduction GO:0007165 IEA
    learning GO:0007612 IMP
    locomotory behavior GO:0007626 IMP
    negative regulation of Arp2/3 complex-mediated actin nucleation GO:0034316 IBA
    actin filament debranching GO:0071846 IBA
    actin filament debranching GO:0071846 IEA
Subcellular Localization
    cortical actin cytoskeleton GO:0030864 IBA
 Experiment description of studies that identified Gmfb in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Gmfb
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MTNR1A  
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
2 Eed  
Affinity Capture-MS Mus musculus
3 Kctd13  
Affinity Capture-MS Mus musculus
4 Rps6ka1 20111
Co-fractionation Mus musculus
5 MTNR1B  
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
View the network image/svg+xml
 Pathways in which Gmfb is involved
No pathways found





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