Experiment description of studies that identified SETSIP in sEVs

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P" Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for SETSIP

Protein Interactor ExoCarta ID Identification method PubMed Species 1 P3H1 64175 Co-fractionation Homo sapiens 2 VAT1 10493 Co-fractionation Homo sapiens 3 UFL1 23376 Affinity Capture-MS Homo sapiens 4 DDRGK1 65992 Affinity Capture-MS Homo sapiens 5 CAPZB 832 Affinity Capture-MS Homo sapiens 6 PPP3CA 5530 Co-fractionation Homo sapiens 7 PFDN1 5201 Co-fractionation Homo sapiens 8 NRD1 4898 Co-fractionation Homo sapiens 9 PPIE 10450 Cross-Linking-MS (XL-MS) Homo sapiens 10 TSN 7247 Co-fractionation Homo sapiens 11 SP110   Affinity Capture-MS Homo sapiens 12 CSNK2A1 1457 Affinity Capture-MS Homo sapiens 13 H1F0 3005 Affinity Capture-MS Homo sapiens 14 SET 6418 Cross-Linking-MS (XL-MS) Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens Cross-Linking-MS (XL-MS) Homo sapiens 15 TCF3   Affinity Capture-MS Homo sapiens 16 HSPA1A 3303 Cross-Linking-MS (XL-MS) Homo sapiens View the network

Pathways in which SETSIP is involved

No pathways found