Gene description for Ruvbl1
Gene name	RuvB-like AAA ATPase 1
Gene symbol	Ruvbl1
Other names/aliases	NMP238 Pontin52 Tip49a
Species	Rattus norvegicus
Database cross references - Ruvbl1
ExoCarta	ExoCarta_65137
Vesiclepedia	VP_65137
Entrez Gene	65137
UniProt	P60123
Ruvbl1 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Ruvbl1

Molecular Function     TFIID-class transcription factor complex binding GO:0001094 ISO     DNA helicase activity GO:0003678 IBA     DNA helicase activity GO:0003678 ISO     DNA clamp loader activity GO:0003689 IEA     transcription coactivator activity GO:0003713 ISO     helicase activity GO:0004386 IEA     ATP binding GO:0005524 IEA     ATP binding GO:0005524 ISO     ATP-dependent activity, acting on DNA GO:0008094 IEA     four-way junction helicase activity GO:0009378 IEA     hydrolase activity GO:0016787 IEA     ATP hydrolysis activity GO:0016887 ISO     ATP hydrolysis activity GO:0016887 ISS     TBP-class protein binding GO:0017025 ISO     double-stranded DNA helicase activity GO:0036121 IEA     3'-5' DNA helicase activity GO:0043138 IDA     ADP binding GO:0043531 ISO     ATPase binding GO:0051117 ISO     forked DNA-dependent helicase activity GO:0061749 IEA     cohesin loader activity GO:0061775 IEA     chromatin extrusion motor activity GO:0140584 IEA     ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA     ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA     single-stranded 3'-5' DNA helicase activity GO:1990518 IEA Biological Process     box C/D snoRNP assembly GO:0000492 IBA     telomere maintenance GO:0000723 ISO     regulation of DNA replication GO:0006275 ISO     DNA repair GO:0006281 IEA     regulation of DNA repair GO:0006282 ISO     DNA recombination GO:0006310 IEA     chromatin remodeling GO:0006338 IBA     chromatin remodeling GO:0006338 ISO     regulation of transcription by RNA polymerase II GO:0006357 IBA     positive regulation of plasminogen activation GO:0010756 IDA     DNA duplex unwinding GO:0032508 IEA     regulation of chromosome organization GO:0033044 ISO     positive regulation of DNA repair GO:0045739 ISO     positive regulation of DNA-templated transcription GO:0045893 ISO     regulation of embryonic development GO:0045995 ISO     cell division GO:0051301 IEA     regulation of cell cycle GO:0051726 ISO     regulation of DNA strand elongation GO:0060382 ISO     positive regulation of canonical Wnt signaling pathway GO:0090263 ISO     telomerase RNA localization to Cajal body GO:0090671 ISO     chromatin looping GO:0140588 IEA     positive regulation of telomere maintenance in response to DNA damage GO:1904507 ISO     positive regulation of double-strand break repair via homologous recombination GO:1905168 ISO     regulation of fibroblast apoptotic process GO:2000269 IMP Subcellular Localization     nucleosome GO:0000786 ISO     Swr1 complex GO:0000812 IBA     Swr1 complex GO:0000812 ISO     Swr1 complex GO:0000812 ISS     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     nucleoplasm GO:0005654 ISO     centrosome GO:0005813 IEA     cytosol GO:0005829 ISO     nuclear matrix GO:0016363 IDA     Ino80 complex GO:0031011 IBA     Ino80 complex GO:0031011 ISO     nuclear membrane GO:0031965 IEA     protein-containing complex GO:0032991 IDA     NuA4 histone acetyltransferase complex GO:0035267 IBA     NuA4 histone acetyltransferase complex GO:0035267 ISO     NuA4 histone acetyltransferase complex GO:0035267 ISS     MLL1 complex GO:0071339 ISO     MLL1 complex GO:0071339 ISS     R2TP complex GO:0097255 IBA     R2TP complex GO:0097255 ISO     R2TP complex GO:0097255 ISS     protein folding chaperone complex GO:0101031 ISO     dynein axonemal particle GO:0120293 ISS     RPAP3/R2TP/prefoldin-like complex GO:1990062 ISO     ribonucleoprotein complex GO:1990904 ISO