Gene description for Ppp1r7
Gene name protein phosphatase 1, regulatory (inhibitor) subunit 7
Gene symbol Ppp1r7
Other names/aliases 2310014J01Rik
SDS22
Species Mus musculus
 Database cross references - Ppp1r7
ExoCarta ExoCarta_66385
Vesiclepedia VP_66385
Entrez Gene 66385
UniProt Q3UM45  
 Ppp1r7 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Ppp1r7
Molecular Function
    protein binding GO:0005515 IPI
    protein phosphatase regulator activity GO:0019888 ISO
Biological Process
    chromosome segregation GO:0007059 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
    chromosome GO:0005694 ISO
 Experiment description of studies that identified Ppp1r7 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Ppp1r7
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
2 PPP1CC 5501
Affinity Capture-MS Homo sapiens
3 PPP1CA 5499
Affinity Capture-MS Homo sapiens
4 Wdr82  
Co-fractionation Mus musculus
5 Eed  
Affinity Capture-MS Mus musculus
6 Wdr92 103784
Co-fractionation Mus musculus
7 Ppp1r2  
Co-fractionation Mus musculus
8 PPP1CB 5500
Affinity Capture-MS Homo sapiens
9 Rprd1b  
Co-fractionation Mus musculus
10 Shank3  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
11 PPP1R11  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which Ppp1r7 is involved
No pathways found





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