Gene description for BPI
Gene name	bactericidal/permeability-increasing protein
Gene symbol	BPI
Other names/aliases	BPIFD1 rBPI
Species	Homo sapiens
Database cross references - BPI
ExoCarta	ExoCarta_671
Vesiclepedia	VP_671
Entrez Gene	671
HGNC	1095
MIM	109195
UniProt	P17213
BPI identified in sEVs derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for BPI

Molecular Function     lipopolysaccharide binding GO:0001530 IBA     lipopolysaccharide binding GO:0001530 IDA Biological Process     antibacterial humoral response GO:0019731 IDA     lipopolysaccharide-mediated signaling pathway GO:0031663 IBA     negative regulation of interleukin-6 production GO:0032715 IBA     negative regulation of interleukin-6 production GO:0032715 IDA     negative regulation of interleukin-8 production GO:0032717 IBA     negative regulation of interleukin-8 production GO:0032717 IDA     negative regulation of tumor necrosis factor production GO:0032720 IBA     negative regulation of tumor necrosis factor production GO:0032720 IDA     negative regulation of macrophage activation GO:0043031 IBA     negative regulation of macrophage activation GO:0043031 IDA     innate immune response GO:0045087 IBA     defense response to Gram-negative bacterium GO:0050829 IBA     defense response to Gram-negative bacterium GO:0050829 IDA     antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA     cellular response to lipopolysaccharide GO:0071222 IDA Subcellular Localization     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IBA     cytoplasmic stress granule GO:0010494 IDA     membrane GO:0016020 IEA     azurophil granule lumen GO:0035578 TAS     specific granule lumen GO:0035580 TAS     extracellular exosome GO:0070062 HDA