Gene description for Rpl37
Gene name ribosomal protein L37
Gene symbol Rpl37
Other names/aliases 3110005M08Rik
Species Mus musculus
 Database cross references - Rpl37
ExoCarta ExoCarta_67281
Vesiclepedia VP_67281
Entrez Gene 67281
UniProt Q9D823  
 Rpl37 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Rpl37
Molecular Function
    RNA binding GO:0003723 IBA
    structural constituent of ribosome GO:0003735 IDA
    structural constituent of ribosome GO:0003735 ISO
    growth factor binding GO:0019838 ISO
    rRNA binding GO:0019843 IEA
    metal ion binding GO:0046872 IEA
    MDM2/MDM4 family protein binding GO:0097371 IEA
    MDM2/MDM4 family protein binding GO:0097371 ISO
    ubiquitin ligase inhibitor activity GO:1990948 IEA
    ubiquitin ligase inhibitor activity GO:1990948 ISO
Biological Process
    cytoplasmic translation GO:0002181 NAS
    translation at presynapse GO:0140236 NAS
    translation at postsynapse GO:0140242 NAS
    positive regulation of signal transduction by p53 class mediator GO:1901798 IEA
    positive regulation of signal transduction by p53 class mediator GO:1901798 ISO
Subcellular Localization
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 TAS
    ribosome GO:0005840 NAS
    cytosolic large ribosomal subunit GO:0022625 IBA
    cytosolic large ribosomal subunit GO:0022625 IDA
    cytosolic large ribosomal subunit GO:0022625 IPI
    cytosolic large ribosomal subunit GO:0022625 ISO
    cytosolic ribosome GO:0022626 ISO
    synapse GO:0045202 EXP
    synapse GO:0045202 IDA
    presynapse GO:0098793 NAS
    postsynapse GO:0098794 NAS
 Experiment description of studies that identified Rpl37 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Rpl37
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Rpl19 19921
Co-fractionation Mus musculus
2 Atg16l1  
Affinity Capture-MS Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml



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