Gene description for Gon4l
Gene name gon-4-like (C.elegans)
Gene symbol Gon4l
Other names/aliases 1500041I23Rik
2610100B20Rik
3632445O20Rik
5430404N14Rik
AA387005
Species Mus musculus
 Database cross references - Gon4l
ExoCarta ExoCarta_76022
Vesiclepedia VP_76022
Entrez Gene 76022
 Gon4l identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Gon4l
Molecular Function
    transcription coregulator activity GO:0003712 IBA
    transcription corepressor activity GO:0003714 IDA
    protein binding GO:0005515 IPI
Biological Process
    regulation of DNA-templated transcription GO:0006355 IBA
    B cell differentiation GO:0030183 IMP
    negative regulation of DNA-templated transcription GO:0045892 IDA
Subcellular Localization
    fibrillar center GO:0001650 ISO
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleus GO:0005634 ISO
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 ISO
    nuclear body GO:0016604 ISO
    Ino80 complex GO:0031011 ISO
 Experiment description of studies that identified Gon4l in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Gon4l
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Sin3a  
Affinity Capture-Western Mus musculus
Affinity Capture-Western Mus musculus
2 Itgb5 16419
Co-fractionation Mus musculus
3 Hdac1 433759
Affinity Capture-Western Mus musculus
4 Yy1 22632
Affinity Capture-Western Mus musculus
Co-fractionation Mus musculus
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Gon4l is involved
No pathways found





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