Gene description for Ppp1r18
Gene name protein phosphatase 1, regulatory subunit 18
Gene symbol Ppp1r18
Other names/aliases 2310014H01Rik
AA407849
AI450394
Species Mus musculus
 Database cross references - Ppp1r18
ExoCarta ExoCarta_76448
Vesiclepedia VP_76448
Entrez Gene 76448
UniProt Q8BQ30  
 Ppp1r18 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ppp1r18
Molecular Function
    molecular_function GO:0003674 ND
    actin binding GO:0003779 IEA
    phosphatase binding GO:0019902 IEA
Biological Process
    biological_process GO:0008150 ND
Subcellular Localization
    cellular_component GO:0005575 ND
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
 Experiment description of studies that identified Ppp1r18 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ppp1r18
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Peak1  
Co-fractionation Mus musculus
2 Tmem173  
Proximity Label-MS Mus musculus
3 Wdr92 103784
Co-fractionation Mus musculus
4 Foxp3  
Affinity Capture-MS Mus musculus
5 Kctd13  
Affinity Capture-MS Mus musculus
6 Pdrg1  
Co-fractionation Mus musculus
7 Atg16l1  
Affinity Capture-MS Mus musculus
8 Fancd2  
Affinity Capture-MS Mus musculus
9 Uri1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Ppp1r18 is involved
No pathways found





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