Gene description for ERI3
Gene name ERI1 exoribonuclease family member 3
Gene symbol ERI3
Other names/aliases PINT1
PRNPIP
Species Homo sapiens
 Database cross references - ERI3
ExoCarta ExoCarta_79033
Vesiclepedia VP_79033
Entrez Gene 79033
HGNC 17276
MIM 609917
UniProt O43414  
 ERI3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for ERI3
Molecular Function
    RNA binding GO:0003723 HDA
    metal ion binding GO:0046872 IEA
 Experiment description of studies that identified ERI3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ERI3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 FNDC3B 64778
Two-hybrid Homo sapiens
3 ARHGAP22 58504
Affinity Capture-MS Homo sapiens
4 TP53 7157
Negative Genetic Homo sapiens
5 NRSN1  
Affinity Capture-MS Homo sapiens
6 C1orf123 54987
Affinity Capture-MS Homo sapiens
7 POLE3  
Affinity Capture-MS Homo sapiens
8 SPX  
Affinity Capture-MS Homo sapiens
9 YTHDF1 54915
Two-hybrid Homo sapiens
10 CENPO  
Two-hybrid Homo sapiens
11 TTK 7272
Co-fractionation Homo sapiens
12 CELF5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 LAMTOR5 10542
Affinity Capture-MS Homo sapiens
14 Cct2 12461
Affinity Capture-MS Mus musculus
15 Cenpf  
Affinity Capture-MS Mus musculus
16 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
17 MT1F  
Affinity Capture-MS Homo sapiens
18 RPA3 6119
Proximity Label-MS Homo sapiens
19 PSMD9 5715
Affinity Capture-MS Homo sapiens
20 CYCS 54205
Co-fractionation Homo sapiens
21 RIN3  
Affinity Capture-MS Homo sapiens
22 KCNJ5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 Stmn1 16765
Affinity Capture-MS Mus musculus
24 Mark2 13728
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which ERI3 is involved
No pathways found





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