Gene description for Actb
Gene name	actin, beta
Gene symbol	Actb
Other names/aliases	Actx
Species	Rattus norvegicus
Database cross references - Actb
ExoCarta	ExoCarta_81822
Vesiclepedia	VP_81822
Entrez Gene	81822
UniProt	P60711
Actb identified in sEVs derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Tracheobronchial cells	19190083
Urine	20535238

Gene ontology annotations for Actb

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     ATP hydrolysis activity GO:0016887 IEA     ATP hydrolysis activity GO:0016887 ISO     kinesin binding GO:0019894 IEA     kinesin binding GO:0019894 ISO     protein kinase binding GO:0019901 IBA     protein kinase binding GO:0019901 IEA     protein kinase binding GO:0019901 IPI     protein kinase binding GO:0019901 ISO     Tat protein binding GO:0030957 IEA     Tat protein binding GO:0030957 ISO     identical protein binding GO:0042802 IEA     identical protein binding GO:0042802 ISO     nitric-oxide synthase binding GO:0050998 IEA     nitric-oxide synthase binding GO:0050998 ISO     structural constituent of postsynaptic actin cytoskeleton GO:0098973 IBA     structural constituent of postsynaptic actin cytoskeleton GO:0098973 IEA     structural constituent of postsynaptic actin cytoskeleton GO:0098973 ISO Biological Process     regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 IMP     morphogenesis of a polarized epithelium GO:0001738 IEA     morphogenesis of a polarized epithelium GO:0001738 ISO     establishment or maintenance of cell polarity GO:0007163 IEA     establishment or maintenance of cell polarity GO:0007163 ISO     axonogenesis GO:0007409 IBA     axonogenesis GO:0007409 IDA     circadian rhythm GO:0007623 IEP     response to mechanical stimulus GO:0009612 IEP     substantia nigra development GO:0021762 ISO     regulation of transmembrane transporter activity GO:0022898 IGI     regulation of transmembrane transporter activity GO:0022898 IMP     regulation of transmembrane transporter activity GO:0022898 ISO     adherens junction assembly GO:0034333 IEA     adherens junction assembly GO:0034333 ISO     response to immobilization stress GO:0035902 IEP     apical protein localization GO:0045176 IEA     apical protein localization GO:0045176 ISO     cell motility GO:0048870 IBA     cell motility GO:0048870 IEA     cell motility GO:0048870 ISO     regulation of norepinephrine uptake GO:0051621 IEA     regulation of norepinephrine uptake GO:0051621 IGI     regulation of norepinephrine uptake GO:0051621 IMP     regulation of norepinephrine uptake GO:0051621 ISO     regulation of cell cycle GO:0051726 IEA     regulation of cell cycle GO:0051726 ISO     retina development in camera-type eye GO:0060041 IEP     platelet aggregation GO:0070527 ISO     cellular response to electrical stimulus GO:0071257 IDA     protein localization to adherens junction GO:0071896 IEA     protein localization to adherens junction GO:0071896 ISO     cellular response to cytochalasin B GO:0072749 IEA     cellular response to cytochalasin B GO:0072749 ISO     postsynaptic actin cytoskeleton organization GO:0098974 IEA     regulation of transepithelial transport GO:0150111 IEA     regulation of transepithelial transport GO:0150111 ISO     regulation of synaptic vesicle endocytosis GO:1900242 IEA     regulation of synaptic vesicle endocytosis GO:1900242 ISO     regulation of protein localization to plasma membrane GO:1903076 IEA     regulation of protein localization to plasma membrane GO:1903076 ISO     positive regulation of double-strand break repair via homologous recombination GO:1905168 IEA     positive regulation of double-strand break repair via homologous recombination GO:1905168 ISO Subcellular Localization     nucleosome GO:0000786 IEA     nucleosome GO:0000786 ISO     stress fiber GO:0001725 IDA     podosome GO:0002102 IDA     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 IEA     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     cytosol GO:0005829 TAS     cytoskeleton GO:0005856 IDA     cytoskeleton GO:0005856 ISO     cytoskeleton GO:0005856 ISS     actin filament GO:0005884 IBA     plasma membrane GO:0005886 ISS     brush border GO:0005903 IEA     brush border GO:0005903 ISO     cell-cell junction GO:0005911 ISO     adherens junction GO:0005912 IEA     adherens junction GO:0005912 ISO     focal adhesion GO:0005925 ISS     actin cytoskeleton GO:0015629 IBA     actin cytoskeleton GO:0015629 ISO     membrane GO:0016020 IBA     lamellipodium GO:0030027 IEA     lamellipodium GO:0030027 ISO     axon GO:0030424 IBA     axon GO:0030424 IDA     cortical cytoskeleton GO:0030863 IEA     cortical cytoskeleton GO:0030863 ISO     protein-containing complex GO:0032991 IDA     protein-containing complex GO:0032991 ISO     NuA4 histone acetyltransferase complex GO:0035267 IBA     NuA4 histone acetyltransferase complex GO:0035267 IEA     NuA4 histone acetyltransferase complex GO:0035267 ISO     cytoplasmic ribonucleoprotein granule GO:0036464 IEA     cytoplasmic ribonucleoprotein granule GO:0036464 ISO     apical junction complex GO:0043296 IEA     apical junction complex GO:0043296 ISO     calyx of Held GO:0044305 IEA     calyx of Held GO:0044305 ISO     membrane raft GO:0045121 IDA     synapse GO:0045202 IBA     tight junction GO:0070160 IEA     tight junction GO:0070160 ISO     dense body GO:0097433 ISS     Schaffer collateral - CA1 synapse GO:0098685 IEA     Schaffer collateral - CA1 synapse GO:0098685 ISO     postsynaptic actin cytoskeleton GO:0098871 IEA     postsynaptic actin cytoskeleton GO:0098871 ISO     glutamatergic synapse GO:0098978 IEA     glutamatergic synapse GO:0098978 ISO     ribonucleoprotein complex GO:1990904 IEA     ribonucleoprotein complex GO:1990904 ISO