Gene description for RNASEH2C
Gene name ribonuclease H2, subunit C
Gene symbol RNASEH2C
Other names/aliases AGS3
AYP1
Species Homo sapiens
 Database cross references - RNASEH2C
ExoCarta ExoCarta_84153
Vesiclepedia VP_84153
Entrez Gene 84153
HGNC 24116
MIM 610330
UniProt Q8TDP1  
 RNASEH2C identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for RNASEH2C
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    mismatch repair GO:0006298 NAS
    RNA catabolic process GO:0006401 IBA
    RNA catabolic process GO:0006401 IDA
Subcellular Localization
    nucleus GO:0005634 IEA
    ribonuclease H2 complex GO:0032299 IBA
    ribonuclease H2 complex GO:0032299 IDA
    ribonuclease H2 complex GO:0032299 IPI
 Experiment description of studies that identified RNASEH2C in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for RNASEH2C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PKMYT1  
Affinity Capture-MS Homo sapiens
2 RNASEH2B  
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 NUDT10  
Affinity Capture-MS Homo sapiens
4 PSMC3 5702
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 CCNB2  
Co-fractionation Homo sapiens
6 HSPA8 3312
Affinity Capture-MS Homo sapiens
7 CTPS2 56474
Affinity Capture-MS Homo sapiens
8 VAC14 55697
Two-hybrid Homo sapiens
9 CAP1 10487
Co-fractionation Homo sapiens
10 ACTC1 70
Affinity Capture-MS Homo sapiens
11 NUBP2 10101
Affinity Capture-MS Homo sapiens
12 OXSR1 9943
Co-fractionation Homo sapiens
13 DLX6  
Affinity Capture-MS Homo sapiens
14 DDX58 23586
Affinity Capture-RNA Homo sapiens
15 Gorasp1  
Affinity Capture-MS Mus musculus
16 RNASEH2A 10535
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CCNB1 891
Co-fractionation Homo sapiens
18 EEF1E1 9521
Co-fractionation Homo sapiens
19 GLUL 2752
Affinity Capture-MS Homo sapiens
20 TLN1 7094
Co-fractionation Homo sapiens
21 SERBP1 26135
Affinity Capture-MS Homo sapiens
22 CBWD7  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which RNASEH2C is involved
No pathways found





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