Gene description for PGLYRP1
Gene name	peptidoglycan recognition protein 1
Gene symbol	PGLYRP1
Other names/aliases	PGLYRP PGRP PGRP-S PGRPS TAG7 TNFSF3L
Species	Homo sapiens
Database cross references - PGLYRP1
ExoCarta	ExoCarta_8993
Vesiclepedia	VP_8993
Entrez Gene	8993
HGNC	8904
MIM	604963
UniProt	O75594
PGLYRP1 identified in sEVs derived from the following tissue/cell type
Urine	19056867

Gene ontology annotations for PGLYRP1

Molecular Function     zinc ion binding GO:0008270 IEA     N-acetylmuramoyl-L-alanine amidase activity GO:0008745 IEA     peptidoglycan immune receptor activity GO:0016019 IBA     peptidoglycan immune receptor activity GO:0016019 IDA     Hsp70 protein binding GO:0030544 IDA     peptidoglycan binding GO:0042834 IBA     peptidoglycan binding GO:0042834 IDA     receptor ligand activity GO:0048018 IDA     molecular adaptor activity GO:0060090 IDA Biological Process     immune response GO:0006955 IBA     signal transduction GO:0007165 IEA     peptidoglycan catabolic process GO:0009253 IEA     detection of bacterium GO:0016045 IDA     killing of cells of another organism GO:0031640 IDA     negative regulation of type II interferon production GO:0032689 IEA     negative regulation of natural killer cell differentiation involved in immune response GO:0032827 IEA     defense response to bacterium GO:0042742 IBA     innate immune response GO:0045087 NAS     negative regulation of inflammatory response GO:0050728 IEA     defense response to Gram-positive bacterium GO:0050830 IDA     biological process involved in interaction with host GO:0051701 IEA     antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA Subcellular Localization     extracellular region GO:0005576 NAS     extracellular region GO:0005576 TAS     extracellular space GO:0005615 IDA     specific granule lumen GO:0035580 TAS     extracellular exosome GO:0070062 HDA     phagocytic vesicle lumen GO:0097013 TAS     tertiary granule lumen GO:1904724 TAS