Gene description for ACAP1
Gene name ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
Gene symbol ACAP1
Other names/aliases CENTB1
Species Homo sapiens
 Database cross references - ACAP1
ExoCarta ExoCarta_9744
Vesiclepedia VP_9744
Entrez Gene 9744
HGNC 16467
MIM 607763
UniProt Q15027  
 ACAP1 identified in sEVs derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for ACAP1
Molecular Function
    GTPase activator activity GO:0005096 IEA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    protein transport GO:0015031 IEA
Subcellular Localization
    membrane GO:0016020 HDA
    recycling endosome membrane GO:0055038 IEA
 Experiment description of studies that identified ACAP1 in sEVs
1
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACAP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 IFFO1  
Two-hybrid Homo sapiens
2 ITGB1 3688
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
3 BOP1 23246
Affinity Capture-MS Homo sapiens
4 RAB11FIP3  
Affinity Capture-Western Homo sapiens
5 AKT1 207
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which ACAP1 is involved
No pathways found





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