Gene description for Ppp2r4
Gene name
protein phosphatase 2A activator, regulatory subunit B
Gene symbol
Ppp2r4
Other names/aliases
2610042B21Rik C77440 N28142 PR53
Species
Mus musculus
Database cross references - Ppp2r4
ExoCarta
ExoCarta_110854
Vesiclepedia
VP_110854
Entrez Gene
110854
UniProt
P58389
Ppp2r4 identified in sEVs derived from the following tissue/cell type
Colon cancer cells
37309723
T-cell lymphoma cells
37309723
Gene ontology annotations for Ppp2r4
Experiment description of studies that identified Ppp2r4 in sEVs
1
Experiment ID
907
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
908
MISEV standards
✔
EM
Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
✔
HSPA5
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
"Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Ppp2r4
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Ppp1ca
19045
Affinity Capture-Western
Mus musculus
2
Ppp2r5b
Co-fractionation
Mus musculus
3
Ppp2ca
19052
Affinity Capture-Western
Mus musculus
4
Strn3
Co-fractionation
Mus musculus
5
Ppp2r5c
26931
Co-fractionation
Mus musculus
6
Igbp1
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Ppp2r4 is involved
No pathways found