Gene description for PGLYRP3
Gene name	peptidoglycan recognition protein 3
Gene symbol	PGLYRP3
Other names/aliases	PGLYRPIalpha PGRP-Ialpha PGRPIA
Species	Homo sapiens
Database cross references - PGLYRP3
ExoCarta	ExoCarta_114771
Vesiclepedia	VP_114771
Entrez Gene	114771
HGNC	30014
MIM	608197
UniProt	Q96LB9
PGLYRP3 identified in sEVs derived from the following tissue/cell type
Hepatocytes	26054723

Gene ontology annotations for PGLYRP3

Molecular Function     protein binding GO:0005515 IPI     zinc ion binding GO:0008270 IEA     N-acetylmuramoyl-L-alanine amidase activity GO:0008745 IEA     peptidoglycan immune receptor activity GO:0016019 IDA     peptidoglycan binding GO:0042834 IDA     protein heterodimerization activity GO:0046982 IPI Biological Process     immune response GO:0006955 IBA     peptidoglycan catabolic process GO:0009253 IEA     detection of bacterium GO:0016045 IDA     killing of cells of another organism GO:0031640 IDA     negative regulation of type II interferon production GO:0032689 IEA     negative regulation of natural killer cell differentiation involved in immune response GO:0032827 IEA     defense response to bacterium GO:0042742 IBA     innate immune response GO:0045087 NAS     defense response to Gram-positive bacterium GO:0050830 IDA     biological process involved in interaction with host GO:0051701 IEA     antimicrobial humoral immune response mediated by antimicrobial peptide GO:0061844 IDA Subcellular Localization     extracellular region GO:0005576 TAS     membrane GO:0016020 NAS     protein-containing complex GO:0032991 IDA