Gene description for STK11IP
Gene name serine/threonine kinase 11 interacting protein
Gene symbol STK11IP
Other names/aliases LIP1
LKB1IP
STK11IP1
Species Homo sapiens
 Database cross references - STK11IP
ExoCarta ExoCarta_114790
Vesiclepedia VP_114790
Entrez Gene 114790
HGNC 19184
MIM 607172
UniProt Q8N1F8  
 STK11IP identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for STK11IP
Molecular Function
    protein kinase binding GO:0019901 IPI
Biological Process
    protein localization GO:0008104 IBA
    protein localization GO:0008104 IDA
Subcellular Localization
    extracellular region GO:0005576 TAS
    cytoplasm GO:0005737 IBA
    cytoplasm GO:0005737 IDA
    lysosomal membrane GO:0005765 HDA
    azurophil granule lumen GO:0035578 TAS
    intracellular membrane-bounded organelle GO:0043231 IDA
 Experiment description of studies that identified STK11IP in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for STK11IP
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ARID1B 57492
Affinity Capture-MS Homo sapiens
2 BRD7  
Affinity Capture-MS Homo sapiens
3 FMOD 2331
Affinity Capture-MS Homo sapiens
4 FBXW11  
Affinity Capture-MS Homo sapiens
5 NAAA  
Affinity Capture-MS Homo sapiens
6 LINGO2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 TMEM106B 54664
Affinity Capture-MS Homo sapiens
8 LAMTOR1 55004
Proximity Label-MS Homo sapiens
9 ARID2  
Affinity Capture-MS Homo sapiens
10 SMARCE1 6605
Affinity Capture-MS Homo sapiens
11 LRRC32 2615
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 KIF14 9928
Affinity Capture-MS Homo sapiens
13 LAMP3  
Proximity Label-MS Homo sapiens
14 NUBP2 10101
Affinity Capture-MS Homo sapiens
15 DPF2  
Affinity Capture-MS Homo sapiens
16 DPF1  
Affinity Capture-MS Homo sapiens
17 RPA2 6118
Proximity Label-MS Homo sapiens
18 SMARCC1 6599
Affinity Capture-MS Homo sapiens
19 GLB1 2720
Affinity Capture-MS Homo sapiens
20 Papss1  
Affinity Capture-MS Mus musculus
21 PBRM1 55193
Affinity Capture-MS Homo sapiens
22 SMARCD1 6602
Affinity Capture-MS Homo sapiens
23 MGARP  
Affinity Capture-MS Homo sapiens
24 TLR4  
Affinity Capture-MS Homo sapiens
25 CUL3 8452
Affinity Capture-MS Homo sapiens
26 SMARCD3  
Affinity Capture-MS Homo sapiens
27 SMAD4  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
28 LAMP2 3920
Proximity Label-MS Homo sapiens
29 GPR55  
Affinity Capture-MS Homo sapiens
30 SS18L1  
Affinity Capture-MS Homo sapiens
31 SMARCD2 6603
Affinity Capture-MS Homo sapiens
32 TLR1 7096
Affinity Capture-MS Homo sapiens
33 SS18  
Affinity Capture-MS Homo sapiens
34 TLR9  
Affinity Capture-MS Homo sapiens
35 STK11 6794
Affinity Capture-Western Homo sapiens
36 COMTD1 118881
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 CDK20  
Affinity Capture-MS Homo sapiens
38 SMARCA4 6597
Affinity Capture-MS Homo sapiens
39 BCL7C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 NTRK1 4914
Affinity Capture-MS Homo sapiens
41 GPR45  
Affinity Capture-MS Homo sapiens
42 RAB7A 7879
Proximity Label-MS Homo sapiens
43 SMARCB1 6598
Affinity Capture-MS Homo sapiens
44 RAB9A 9367
Proximity Label-MS Homo sapiens
45 DPF3  
Affinity Capture-MS Homo sapiens
46 TLR2 7097
Affinity Capture-MS Homo sapiens
47 MEOX2  
Two-hybrid Homo sapiens
48 SMARCA2 6595
Affinity Capture-MS Homo sapiens
49 KERA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 ARID1A 8289
Affinity Capture-MS Homo sapiens
51 PHF10  
Affinity Capture-MS Homo sapiens
52 ISLR 3671
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 VASN 114990
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 THTPA  
Affinity Capture-MS Homo sapiens
55 MAPK8 5599
Affinity Capture-MS Homo sapiens
56 SRP14 6727
Affinity Capture-MS Homo sapiens
57 BRD9 65980
Affinity Capture-MS Homo sapiens
58 RHOB 388
Proximity Label-MS Homo sapiens
59 GLTSCR1 29998
Affinity Capture-MS Homo sapiens
60 TMEM192 201931
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 COMMD1 150684
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which STK11IP is involved
PathwayEvidenceSource
Immune System TAS Reactome
Innate Immune System TAS Reactome
Neutrophil degranulation TAS Reactome





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