Gene description for Ccng1
Gene name cyclin G1
Gene symbol Ccng1
Other names/aliases AI314029
Species Mus musculus
 Database cross references - Ccng1
ExoCarta ExoCarta_12450
Vesiclepedia VP_12450
Entrez Gene 12450
UniProt P51945  
 Ccng1 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ccng1
Molecular Function
    cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 IBA
Biological Process
    G1/S transition of mitotic cell cycle GO:0000082 IBA
    syncytium formation GO:0006949 IEA
    syncytium formation GO:0006949 ISO
    mitotic G2 DNA damage checkpoint signaling GO:0007095 IEA
    mitotic G2 DNA damage checkpoint signaling GO:0007095 ISO
    response to gravity GO:0009629 IEA
    negative regulation of apoptotic process GO:0043066 IEA
    negative regulation of apoptotic process GO:0043066 ISO
    cell division GO:0051301 IEA
Subcellular Localization
    cyclin-dependent protein kinase holoenzyme complex GO:0000307 IBA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IBA
    dendrite GO:0030425 IEA
    dendrite GO:0030425 ISO
    neuronal cell body GO:0043025 IEA
    neuronal cell body GO:0043025 ISO
    perinuclear region of cytoplasm GO:0048471 IEA
    perinuclear region of cytoplasm GO:0048471 ISO
 Experiment description of studies that identified Ccng1 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ccng1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP2CA 5515
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
2 Mdm2  
Affinity Capture-Western Mus musculus
Reconstituted Complex Mus musculus
Reconstituted Complex Mus musculus
3 PPP2R1A 5518
Co-fractionation Homo sapiens
4 Trp53  
Affinity Capture-Western Mus musculus
5 PPP2R5A 5525
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
View the network image/svg+xml



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